Literature DB >> 27080415

Racial and ethnic disparities in outcomes after heart transplantation: A systematic review of contributing factors and future directions to close the outcomes gap.

Alanna A Morris1, Evan P Kransdorf2, Bernice L Coleman3, Monica Colvin4.   

Abstract

The demographics of patients undergoing heart transplantation in the United States have shifted over the last 10 years, with an increasing number of racial and ethnic minorities undergoing heart transplant. Multiple studies have shown that survival of African American patients after heart transplantation is lower compared with other ethnic groups. We review the data supporting the presence of this outcome disparity and examine the multiple mechanisms that contribute. With an increasingly diverse population in the United States, knowledge of these disparities, their mechanisms, and ways to improve outcomes is essential.
Copyright © 2016 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  LVAD; cardiomyopathy; health disparities; heart transplantation; race/ethnicity

Mesh:

Year:  2016        PMID: 27080415      PMCID: PMC6512959          DOI: 10.1016/j.healun.2016.01.1231

Source DB:  PubMed          Journal:  J Heart Lung Transplant        ISSN: 1053-2498            Impact factor:   10.247


  58 in total

1.  Genetic structure of human populations.

Authors:  Noah A Rosenberg; Jonathan K Pritchard; James L Weber; Howard M Cann; Kenneth K Kidd; Lev A Zhivotovsky; Marcus W Feldman
Journal:  Science       Date:  2002-12-20       Impact factor: 47.728

2.  Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies.

Authors:  Hua Tang; Tom Quertermous; Beatriz Rodriguez; Sharon L R Kardia; Xiaofeng Zhu; Andrew Brown; James S Pankow; Michael A Province; Steven C Hunt; Eric Boerwinkle; Nicholas J Schork; Neil J Risch
Journal:  Am J Hum Genet       Date:  2004-12-29       Impact factor: 11.025

Review 3.  Gene-environment interactions in human diseases.

Authors:  David J Hunter
Journal:  Nat Rev Genet       Date:  2005-04       Impact factor: 53.242

4.  Transplanting the highly sensitized patient: The emory algorithm.

Authors:  R A Bray; J D L Nolen; C Larsen; T Pearson; K A Newell; K Kokko; A Guasch; P Tso; J B Mendel; H M Gebel
Journal:  Am J Transplant       Date:  2006-08-25       Impact factor: 8.086

5.  Peripheral blood antigen-presenting cells from African-Americans exhibit increased CD80 and CD86 expression.

Authors:  A Hutchings; W M Purcell; M R Benfield
Journal:  Clin Exp Immunol       Date:  1999-11       Impact factor: 4.330

6.  To induce or not to induce: do patients at greatest risk for fatal rejection benefit from cytolytic induction therapy?

Authors:  R Higgins; J K Kirklin; R N Brown; B K Rayburn; L Wagoner; R Oren; L Miller; M Flattery; R C Bourge
Journal:  J Heart Lung Transplant       Date:  2005-04       Impact factor: 10.247

7.  Survival and incidence of acute rejection in heart transplant recipients undergoing successful withdrawal from steroid therapy.

Authors:  Thomas O Felkel; Andrew L Smith; Hermann C Reichenspurner; Bonnie LaFleur; Jerre F Lutz; Kirk R Kanter; Michael B Gravanis; Thomas S Johnston
Journal:  J Heart Lung Transplant       Date:  2002-05       Impact factor: 10.247

8.  Payment for immunosuppression after organ transplantation. American Society of Transplantation.

Authors:  B L Kasiske; D Cohen; M R Lucey; J F Neylan
Journal:  JAMA       Date:  2000-05-10       Impact factor: 56.272

9.  Influence of race on kidney transplant outcomes within and outside the Department of Veterans Affairs.

Authors:  Harini A Chakkera; Ann M O'Hare; Kirsten L Johansen; Denise Hynes; Kevin Stroupe; Philip M Colin; Glenn M Chertow
Journal:  J Am Soc Nephrol       Date:  2004-11-24       Impact factor: 10.121

10.  Ethnic disparity in clinical outcome after heart transplantation is abrogated using tacrolimus and mycophenolate mofetil-based immunosuppression.

Authors:  Mandeep R Mehra; Patricia A Uber; Robert L Scott; Myung H Park
Journal:  Transplantation       Date:  2002-12-15       Impact factor: 4.939

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  17 in total

Review 1.  Health Disparities in Kidney Transplantation for African Americans.

Authors:  Kimberly Harding; Tesfaye B Mersha; Phuong-Thu Pham; Amy D Waterman; Fern A Webb; Joseph A Vassalotti; Susanne B Nicholas
Journal:  Am J Nephrol       Date:  2017-08-05       Impact factor: 3.754

2.  Indications for and outcomes of therapeutic plasma exchange after cardiac transplantation: A single center retrospective study.

Authors:  Oluwatoyosi A Onwuemene; Steven C Grambow; Chetan B Patel; Robert J Mentz; Carmelo A Milano; Joseph G Rogers; Ara D Metjian; Gowthami M Arepally; Thomas L Ortel
Journal:  J Clin Apher       Date:  2018-03-10       Impact factor: 2.821

3.  Circulating microRNAs in cellular and antibody-mediated heart transplant rejection.

Authors:  Palak Shah; Sean Agbor-Enoh; Pramita Bagchi; Christopher R deFilippi; Angela Mercado; Gouqing Diao; Dave Jp Morales; Keyur B Shah; Samer S Najjar; Erika Feller; Steven Hsu; Maria E Rodrigo; Sabra C Lewsey; Moon Kyoo Jang; Charles Marboe; Gerald J Berry; Kiran K Khush; Hannah A Valantine
Journal:  J Heart Lung Transplant       Date:  2022-06-28       Impact factor: 13.569

4.  Racial disparities in long-term survival after heart transplantation: What should we be telling patients?

Authors:  Alexis K Okoh; Jeffrey Wang; Apoorva Gangavelli; Rebecca Steinberg; Aditi Nayak; Divya Gupta; Mani Daneshmand; Alanna A Morris
Journal:  Clin Transplant       Date:  2022-07-08       Impact factor: 3.456

5.  Racial Disparities in Hospital Mortality Among Pediatric Cardiomyopathy and Myocarditis Patients.

Authors:  Jillian Olsen; Yuen Lie Tjoeng; Joshua Friedland-Little; Titus Chan
Journal:  Pediatr Cardiol       Date:  2020-10-06       Impact factor: 1.655

6.  End-stage renal disease after pediatric heart transplantation: A 25-year national cohort study.

Authors:  Swati Choudhry; Vikas R Dharnidharka; Chesney D Castleberry; Charles W Goss; Kathleen E Simpson; Kenneth B Schechtman; Charles E Canter
Journal:  J Heart Lung Transplant       Date:  2017-10-02       Impact factor: 10.247

7.  County socioeconomic characteristics and heart transplant outcomes in the United States.

Authors:  Dmitry Tumin; Jessica Horan; Emily A Shrider; Sakima A Smith; Joseph D Tobias; Don Hayes; Randi E Foraker
Journal:  Am Heart J       Date:  2017-06-03       Impact factor: 4.749

Review 8.  Racial/Ethnic and Gender Disparities in Heart Failure with Reduced Ejection Fraction.

Authors:  Hunter Mwansa; Sabra Lewsey; Sula Mazimba; Khadijah Breathett
Journal:  Curr Heart Fail Rep       Date:  2021-03-05

9.  Better Understanding the Disparity Associated With Black Race in Heart Transplant Outcomes: A National Registry Analysis.

Authors:  Hasina Maredia; Mary Grace Bowring; Allan B Massie; Sunjae Bae; Amber Kernodle; Shakirat Oyetunji; Christian Merlo; Robert S D Higgins; Dorry L Segev; Errol L Bush
Journal:  Circ Heart Fail       Date:  2021-02-02       Impact factor: 8.790

10.  Increased Incidence of Chronic Kidney Injury in African Americans Following Cardiac Transplantation.

Authors:  Joseph Bayne; Michael Francke; Elaine Ma; Geoffrey A Rubin; Uma Mahesh R Avula; Haajra Baksh; Raymond Givens; Elaine Y Wan
Journal:  J Racial Ethn Health Disparities       Date:  2020-10-28
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