Literature DB >> 27076070

Are Metformin Doses Used in Murine Cancer Models Clinically Relevant?

Navdeep S Chandel1, Dania Avizonis2, Colleen R Reczek3, Samuel E Weinberg3, Stephan Menz4, Roland Neuhaus4, Sven Christian5, Andrea Haegebarth5, Carolyn Algire5, Michael Pollak6.   

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Year:  2016        PMID： 27076070     DOI： 10.1016/j.cmet.2016.03.010

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


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  80 in total

1.  Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex.

Authors:  Jessica J Howell; Kristina Hellberg; Marc Turner; George Talbott; Matthew J Kolar; Debbie S Ross; Gerta Hoxhaj; Alan Saghatelian; Reuben J Shaw; Brendan D Manning
Journal:  Cell Metab       Date:  2017-01-12       Impact factor: 27.287

Review 2.  Pyridine Dinucleotides from Molecules to Man.

Authors:  Joshua P Fessel; William M Oldham
Journal:  Antioxid Redox Signal       Date:  2017-07-25       Impact factor: 8.401

Review 3.  The effects of metformin on gut microbiota and the immune system as research frontiers.

Authors:  Michael Pollak
Journal:  Diabetologia       Date:  2017-08-02       Impact factor: 10.122

4.  Modified Metformin as a More Potent Anticancer Drug: Mitochondrial Inhibition, Redox Signaling, Antiproliferative Effects and Future EPR Studies.

Authors:  Balaraman Kalyanaraman; Gang Cheng; Micael Hardy; Olivier Ouari; Adam Sikora; Jacek Zielonka; Michael B Dwinell
Journal:  Cell Biochem Biophys       Date:  2017-04-21       Impact factor: 2.194

5.  Targeting liver stage malaria with metformin.

Authors:  Iset Medina Vera; Margarida T Grilo Ruivo; Leonardo F Lemos Rocha; Sofia Marques; Sangeeta N Bhatia; Maria M Mota; Liliana Mancio-Silva
Journal:  JCI Insight       Date:  2019-12-19

Review 6.  Mitochondrial Metabolism as a Target for Cancer Therapy.

Authors:  Karthik Vasan; Marie Werner; Navdeep S Chandel
Journal:  Cell Metab       Date:  2020-07-14       Impact factor: 27.287

7.  Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria.

Authors:  Zhijun Guo; Irina F Sevrioukova; Ilia G Denisov; Xia Zhang; Ting-Lan Chiu; Dafydd G Thomas; Eric A Hanse; Rebecca A D Cuellar; Yelena V Grinkova; Vanessa Wankhede Langenfeld; Daniel S Swedien; Justin D Stamschror; Juan Alvarez; Fernando Luna; Adela Galván; Young Kyung Bae; Julia D Wulfkuhle; Rosa I Gallagher; Emanuel F Petricoin; Beverly Norris; Craig M Flory; Robert J Schumacher; M Gerard O'Sullivan; Qing Cao; Haitao Chu; John D Lipscomb; William M Atkins; Kalpna Gupta; Ameeta Kelekar; Ian A Blair; Jorge H Capdevila; John R Falck; Stephen G Sligar; Thomas L Poulos; Gunda I Georg; Elizabeth Ambrose; David A Potter
Journal:  Cell Chem Biol       Date:  2017-09-14       Impact factor: 8.116

8.  Metformin Targets Central Carbon Metabolism and Reveals Mitochondrial Requirements in Human Cancers.

Authors:  Xiaojing Liu; Iris L Romero; Lacey M Litchfield; Ernst Lengyel; Jason W Locasale
Journal:  Cell Metab       Date:  2016-10-13       Impact factor: 27.287

9.  Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis.

Authors:  Saul Soberanes; Alexander V Misharin; Amit Jairaman; Luisa Morales-Nebreda; Alexandra C McQuattie-Pimentel; Takugo Cho; Robert B Hamanaka; Angelo Y Meliton; Paul A Reyfman; James M Walter; Ching-I Chen; Monica Chi; Stephen Chiu; Francisco J Gonzalez-Gonzalez; Matthew Antalek; Hiam Abdala-Valencia; Sergio E Chiarella; Kaitlyn A Sun; Parker S Woods; Andrew J Ghio; Manu Jain; Harris Perlman; Karen M Ridge; Richard I Morimoto; Jacob I Sznajder; William E Balch; Sangeeta M Bhorade; Ankit Bharat; Murali Prakriya; Navdeep S Chandel; Gökhan M Mutlu; G R Scott Budinger
Journal:  Cell Metab       Date:  2018-10-11       Impact factor: 27.287

10.  The Liver Circadian Clock Modulates Biochemical and Physiological Responses to Metformin.

Authors:  Emma Henriksson; Anne-Laure Huber; Erin K Soto; Anna Kriebs; Megan E Vaughan; Drew Duglan; Alanna B Chan; Stephanie J Papp; Madelena Nguyen; Megan E Afetian; Katja A Lamia
Journal:  J Biol Rhythms       Date:  2017-06-15       Impact factor: 3.182
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