| Literature DB >> 27075872 |
Akshay S Desai1, Pardeep S Jhund2.
Abstract
Although patients with heart failure and preserved ejection fraction (HF-PEF) represent nearly half of the population with chronic heart failure, few evidence-based medical therapies are available. The neutral overall results of the TOPCAT trial of spironolactone in HF-PEF leave clinicians who treat heart failure with an ongoing clinical dilemma. In this review, we outline an approach to the clinical management of the patient with HF-PEF synthesizing data from available clinical trials and expert consensus. Published on behalf of the European Society of Cardiology. All rights reserved.Entities:
Keywords: Clinical management; Heart failure with preserved ejection fraction; Spironolactone
Mesh:
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Year: 2016 PMID: 27075872 DOI: 10.1093/eurheartj/ehw114
Source DB: PubMed Journal: Eur Heart J ISSN: 0195-668X Impact factor: 29.983