Literature DB >> 29520392

Current themes in myocardial and coronary vascular aging.

Amanda J LeBlanc1, Natia Q Kelm1, Monika George1.   

Abstract

Advancing age will affect every individual and its impact on cardiac health deserves significant attention. The age-related physiological changes occurring in the coronary vasculature, myocardium, and valves set the stage upon which cardiovascular disease can escalate in the elderly population. The overall focus of this review is to highlight new and noteworthy studies and to incorporate reviews related to cardiac senescence in the context of the current state of the field. Lastly, future directions in the field of cardiac aging and the development of novel therapeutics to treat pathophysiological conditions typically associated with advancing age will be discussed.

Entities:  

Keywords:  aging; cardiac; coronary; microvascular; perfusion; senescence

Year:  2017        PMID： 29520392      PMCID： PMC5837072          DOI： 10.1016/j.cophys.2017.07.001

Source DB:  PubMed          Journal:  Curr Opin Physiol        ISSN： 2468-8673


  51 in total

Review 1.  Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part III: cellular and molecular clues to heart and arterial aging.

Authors:  Edward G Lakatta
Journal:  Circulation       Date:  2003-01-28       Impact factor: 29.690

2.  Stress echocardiography for risk assessment in octogenarians.

Authors:  Lauro Cortigiani; Riccardo Bigi; Francesco Bovenzi; Eugenio Picano; Rosa Sicari
Journal:  Int J Cardiol       Date:  2012-11-30       Impact factor: 4.164

Review 3.  Epidemiology of heart failure with preserved ejection fraction.

Authors:  Shannon M Dunlay; Véronique L Roger; Margaret M Redfield
Journal:  Nat Rev Cardiol       Date:  2017-05-11       Impact factor: 32.419

4.  Relation of Mitral Valve Surgery Volume to Repair Rate, Durability, and Survival.

Authors:  Joanna Chikwe; Nana Toyoda; Anelechi C Anyanwu; Shinobu Itagaki; Natalia N Egorova; Percy Boateng; Ahmed El-Eshmawi; David H Adams
Journal:  J Am Coll Cardiol       Date:  2017-04-24       Impact factor: 24.094

5.  Transgenic overexpression of macrophage matrix metalloproteinase-9 exacerbates age-related cardiac hypertrophy, vessel rarefaction, inflammation, and fibrosis.

Authors:  Hiroe Toba; Presley L Cannon; Andriy Yabluchanskiy; Rugmani Padmanabhan Iyer; Jeanine D'Armiento; Merry L Lindsey
Journal:  Am J Physiol Heart Circ Physiol       Date:  2016-12-23       Impact factor: 4.733

Review 6.  Mitochondrial Metabolism in Aging Heart.

Authors:  Edward J Lesnefsky; Qun Chen; Charles L Hoppel
Journal:  Circ Res       Date:  2016-05-13       Impact factor: 17.367

7.  Myocardial aging as a T-cell-mediated phenomenon.

Authors:  Gustavo Campos Ramos; Anne van den Berg; Vânia Nunes-Silva; Johannes Weirather; Laura Peters; Matthias Burkard; Mike Friedrich; Jürgen Pinnecker; Marco Abeßer; Katrin G Heinze; Kai Schuh; Niklas Beyersdorf; Thomas Kerkau; Jocelyne Demengeot; Stefan Frantz; Ulrich Hofmann
Journal:  Proc Natl Acad Sci U S A       Date:  2017-03-02       Impact factor: 11.205

8.  Aging impairs flow-induced dilation in coronary arterioles: role of NO and H(2)O(2).

Authors:  Lori S Kang; Rafael A Reyes; Judy M Muller-Delp
Journal:  Am J Physiol Heart Circ Physiol       Date:  2009-07-17       Impact factor: 4.733

9.  Age impairs Flk-1 signaling and NO-mediated vasodilation in coronary arterioles.

Authors:  Amanda J LeBlanc; Robert D Shipley; Lori S Kang; Judy M Muller-Delp
Journal:  Am J Physiol Heart Circ Physiol       Date:  2008-10-03       Impact factor: 4.733

Review 10.  Expert consensus document: Mitochondrial function as a therapeutic target in heart failure.

Authors:  David A Brown; Justin B Perry; Mitchell E Allen; Hani N Sabbah; Brian L Stauffer; Saame Raza Shaikh; John G F Cleland; Wilson S Colucci; Javed Butler; Adriaan A Voors; Stefan D Anker; Bertram Pitt; Burkert Pieske; Gerasimos Filippatos; Stephen J Greene; Mihai Gheorghiade
Journal:  Nat Rev Cardiol       Date:  2016-12-22       Impact factor: 32.419
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