Literature DB >> 27075651

Time-to-treatment of mental disorders in a community sample of Dutch adolescents. A TRAILS study.

D Raven1, F Jörg1, E Visser2, A J Oldehinkel1, R A Schoevers1.   

Abstract

AIMS: Timely recognition and treatment of mental disorders with an onset in childhood and adolescence is paramount, as these are characterized by greater severity and longer persistence than disorders with an onset in adulthood. Studies examining time-to-treatment, also referred to as treatment delay, duration of untreated illness or latency to treatment, and defined as the time between disorder onset and initial treatment contact, are sparse and all based on adult samples. The aim of this study was to describe time-to-treatment and its correlates for any health care professional (any care) and secondary mental health care (secondary care), for a broad range of mental disorders, in adolescents.
METHODS: Data from the Dutch community-based cohort study TRacking Adolescents' Individual Lives Survey (TRAILS; N = 2230) were used. The Composite International Diagnostic Interview (CIDI) was administered to assess DSM-IV disorders, the age of onset, and the age of initial treatment contact with any health care professional in 1584 adolescents of 18-20 years old. In total 43% of the adolescents (n = 675) were diagnosed with a lifetime DSM-IV disorder. The age of initial treatment contact with secondary care was based on administrative records from 321 adolescents without a disorder onset before the age of 10. Descriptive statistics, cumulative lifetime probability plots, and Cox regression analyses were used analyze time-to-treatment.
RESULTS: The proportion of adolescents who reported lifetime treatment contact with any care varied from 15% for alcohol dependence to 82% for dysthymia. Regarding secondary care, proportions of lifetime treatment contact were lower for mood disorders and higher for substance dependence. Time-to-treatment for any care varied considerably between and within diagnostic classes. The probability of lifetime treatment contact for mood disorders was above 90%, whereas for other mental disorders this was substantially lower. An earlier age of onset predicted a longer, and the presence of a co-morbid mood disorder predicted a shorter time-to-treatment in general. Disorder severity predicted a shorter time-to-treatment for any care, but not for secondary care. Time-to-treatment for secondary care was shorter for adolescents from low and middle socioeconomic background than for adolescents from a high socioeconomic background.
CONCLUSION: Although the time-to-treatment was shorter for adolescents than for adults, it was still substantial, and the overall patterns were remarkably similar to those found in adults. Efforts to reduce time-to-treatment should therefore be aimed at children and adolescents. Future research should address mechanisms underlying time-to-treatment and its consequences for early-onset disorders in particular.

Entities:  

Keywords:  Adolescence; diagnosis; health service research; mental health; survival analysis

Mesh:

Year:  2016        PMID: 27075651      PMCID: PMC6998684          DOI: 10.1017/S2045796016000226

Source DB:  PubMed          Journal:  Epidemiol Psychiatr Sci        ISSN: 2045-7960            Impact factor:   6.892


  43 in total

1.  The World Mental Health (WMH) Survey Initiative Version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI).

Authors:  Ronald C Kessler; T Bedirhan Ustün
Journal:  Int J Methods Psychiatr Res       Date:  2004       Impact factor: 4.035

2.  Lifetime prevalence of mental health disorders and delay in treatment following initial onset: evidence from the Northern Ireland Study of Health and Stress.

Authors:  B P Bunting; S D Murphy; S M O'Neill; F R Ferry
Journal:  Psychol Med       Date:  2011-11-25       Impact factor: 7.723

3.  Evaluation of non-response bias in mental health determinants and outcomes in a large sample of pre-adolescents.

Authors:  Andrea F de Winter; Albertine J Oldehinkel; René Veenstra; J Agnes Brunnekreef; Frank C Verhulst; Johan Ormel
Journal:  Eur J Epidemiol       Date:  2005       Impact factor: 8.082

4.  Patterns and predictors of treatment contact after first onset of psychiatric disorders.

Authors:  R C Kessler; M Olfson; P A Berglund
Journal:  Am J Psychiatry       Date:  1998-01       Impact factor: 18.112

5.  Failure and delay in initial treatment contact after first onset of mental disorders in the National Comorbidity Survey Replication.

Authors:  Philip S Wang; Patricia Berglund; Mark Olfson; Harold A Pincus; Kenneth B Wells; Ronald C Kessler
Journal:  Arch Gen Psychiatry       Date:  2005-06

6.  Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication.

Authors:  Ronald C Kessler; Patricia Berglund; Olga Demler; Robert Jin; Kathleen R Merikangas; Ellen E Walters
Journal:  Arch Gen Psychiatry       Date:  2005-06

7.  Concordance of the Composite International Diagnostic Interview Version 3.0 (CIDI 3.0) with standardized clinical assessments in the WHO World Mental Health surveys.

Authors:  Josep Maria Haro; Saena Arbabzadeh-Bouchez; Traolach S Brugha; Giovanni de Girolamo; Margaret E Guyer; Robert Jin; Jean Pierre Lepine; Fausto Mazzi; Blanca Reneses; Gemma Vilagut; Nancy A Sampson; Ronald C Kessler
Journal:  Int J Methods Psychiatr Res       Date:  2006       Impact factor: 4.035

Review 8.  Age of onset of mental disorders: a review of recent literature.

Authors:  Ronald C Kessler; G Paul Amminger; Sergio Aguilar-Gaxiola; Jordi Alonso; Sing Lee; T Bedirhan Ustün
Journal:  Curr Opin Psychiatry       Date:  2007-07       Impact factor: 4.741

Review 9.  Duration of untreated illness and outcomes in unipolar depression: a systematic review and meta-analysis.

Authors:  Lucio Ghio; Simona Gotelli; Maurizio Marcenaro; Mario Amore; Werner Natta
Journal:  J Affect Disord       Date:  2013-10-21       Impact factor: 4.839

Review 10.  Age of onset of mental disorders and use of mental health services: needs, opportunities and obstacles.

Authors:  G de Girolamo; J Dagani; R Purcell; A Cocchi; P D McGorry
Journal:  Epidemiol Psychiatr Sci       Date:  2012-03       Impact factor: 7.818

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2.  A Game-Based School Program for Mental Health Literacy and Stigma on Depression (Moving Stories): Cluster Randomized Controlled Trial.

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3.  Mismatch negativity of preschool children at risk of developing mental health problems.

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