Literature DB >> 270697

Synthesis and secretion of a high molecular weight form of nerve growth factor by skeletal muscle cells in culture.

R A Murphy, R H Singer, J D Saide, N J Pantazis, M H Blanchard, K S Byron, B G Arnason, M Young.   

Abstract

Rat skeletal muscle cells and a cloned myogenic cell line synthesize and secrete in culture a molecule that is immunologically and biologically indistinguishable from the active form of nerve growth factor (NGF) from mouse submandibular gland. This protein can be detected in medium conditioned by muscle cells both before and after fusion and in the soluble fraction of muscle cell homogenates. Chromatographic data also reveal that the molecular properties of muscle cell NGF differ from those of the growth factor purified from mouse submandibular glands. Muscle cell NGF has a molecular weight between 140,000 and 160,000, whereas purified mouse gland NGF has a molecular weight of 26,000. The biologic function of muscle cell NGF is not known, although it could be that it plays some role relating to the association of nerves and muscle in vivo.

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Year:  1977        PMID： 270697      PMCID： PMC431970          DOI： 10.1073/pnas.74.10.4496

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  18 in total

1.  The growth of cells on a transparent gel of reconstituted rat-tail collagen.

Authors:  R L EHRMANN; G O GEY
Journal:  J Natl Cancer Inst       Date:  1956-06       Impact factor: 13.506

2.  Molecular size of nerve growth factor in dilute solution.

Authors:  M Young; J D Saide; R A Murphy; B G Arnason
Journal:  J Biol Chem       Date:  1976-01-25       Impact factor: 5.157

3.  Amino acid sequences of mouse 2.5S nerve growth factor. II. Isolation and characterization of the thermolytic and peptic peptides and the complete covalent structure.

Authors:  R H Angeletti; M A Hermodson; R A Bradshaw
Journal:  Biochemistry       Date:  1973-01-02       Impact factor: 3.162

4.  Synapse formation between dissociated nerve and muscle cells in low density cell cultures.

Authors:  G D Fischbach
Journal:  Dev Biol       Date:  1972-06       Impact factor: 3.582

5.  Alterations of enzymatic activities during muscle differentiation in vitro.

Authors:  A Shainberg; G Yagil; D Yaffe
Journal:  Dev Biol       Date:  1971-05       Impact factor: 3.582

6.  The effect of-beta-D-arabinofuranosylcytosine on growth, viability, and DNA synthesis of mouse L-cells.

Authors:  F L Graham; G F Whitmore
Journal:  Cancer Res       Date:  1970-11       Impact factor: 12.701

7.  Synthesis of nerve growth factor by L and 3T3 cells in culture.

Authors:  J Oger; B G Arnason; N Pantazis; J Lehrich; M Young
Journal:  Proc Natl Acad Sci U S A       Date:  1974-04       Impact factor: 11.205

8.  Choline acetyltransferase activity is increased in combined cultures of spinal cord and muscle cells from mice.

Authors:  E L Giller; B K Schrier; A Shainberg; H R Fisk; P G Nelson
Journal:  Science       Date:  1973-11-09       Impact factor: 47.728

9.  Dissociation of the 7S-nerve growth factor complex in solution.

Authors:  N J Pantazis; R A Murphy; J D Saide; M H Blanchard; M Young
Journal:  Biochemistry       Date:  1977-04-05       Impact factor: 3.162

10.  Molecular properties of the nerve growth factor secreted by L cells.

Authors:  N J Pantazis; M H Blanchard; B G Arnason; M Young
Journal:  Proc Natl Acad Sci U S A       Date:  1977-04       Impact factor: 11.205
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  9 in total

1.  A method for the quantitative analysis of nerve growth in vitro.

Authors:  H M Liu; K Schmid
Journal:  In Vitro Cell Dev Biol       Date:  1988-03

Review 2.  The mouse submaxillary gland: a model for the study of hormonally dependent growth factors.

Authors:  P Walker
Journal:  J Endocrinol Invest       Date:  1982 May-Jun       Impact factor: 4.256

3.  Neurite outgrowth from embryonic chicken spinal neurons is promoted by media conditioned by muscle cells.

Authors:  C E Henderson; M Huchet; J P Changeux
Journal:  Proc Natl Acad Sci U S A       Date:  1981-04       Impact factor: 11.205

4.  Tissue engineering the mechanosensory circuit of the stretch reflex arc: sensory neuron innervation of intrafusal muscle fibers.

Authors:  John W Rumsey; Mainak Das; Abhijeet Bhalkikar; Maria Stancescu; James J Hickman
Journal:  Biomaterials       Date:  2010-08-13       Impact factor: 12.479

5.  Myoblasts and myoblast-conditioned medium attract the earliest spinal neurites from frog embryos.

Authors:  C D McCaig
Journal:  J Physiol       Date:  1986-06       Impact factor: 5.182

6.  Isolated hepatic granulomas from mice infected with Schistosoma mansoni contain nerve growth factor.

Authors:  G W Varilek; J V Weinstock; N J Pantazis
Journal:  Infect Immun       Date:  1991-12       Impact factor: 3.441

7.  Tissue engineering intrafusal fibers: dose- and time-dependent differentiation of nuclear bag fibers in a defined in vitro system using neuregulin 1-beta-1.

Authors:  John W Rumsey; Mainak Das; Jung-Fong Kang; Robert Wagner; Peter Molnar; James J Hickman
Journal:  Biomaterials       Date:  2008-03       Impact factor: 12.479

8.  Repeated muscle injury as a presumptive trigger for chronic masticatory muscle pain.

Authors:  Dean Dessem; Richard M Lovering
Journal:  Pain Res Treat       Date:  2011-06-12

9.  Microglia activation as a biomarker for traumatic brain injury.

Authors:  Diana G Hernandez-Ontiveros; Naoki Tajiri; Sandra Acosta; Brian Giunta; Jun Tan; Cesar V Borlongan
Journal:  Front Neurol       Date:  2013-03-26       Impact factor: 4.003
  9 in total

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