Literature DB >> 27057430

Immunosurveillance in esophageal carcinoma: The decisive impact of regulatory T cells.

Erika Vacchelli1, Michaela Semeraro2, Julien Adam3, Peggy Dartigues4, Laurence Zitvogel5, Guido Kroemer6.   

Abstract

Neoadjuvant radiochemotherapy of esophageal carcinomas causes a variable degree of depletion of tumor-infiltrating FOXP3+ regulatory T cells (Tregs). The frequency of local Tregs in the operative specimens negatively correlates with the pathological response and overall patient survival. These results underscore the importance of immunosurveillance in determining the fate of patients with esophageal cancers treated with radiochemotherapy.

Entities:  

Keywords:  Apoptosis; CTL; Treg ; immunogenic cell death; pattern recognition receptor

Year:  2015        PMID： 27057430      PMCID： PMC4801440          DOI： 10.1080/2162402X.2015.1064581

Source DB:  PubMed          Journal:  Oncoimmunology        ISSN： 2162-4011            Impact factor:   8.110


  9 in total

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Journal:  Cancer Res       Date:  2015-05-21       Impact factor: 12.701

2.  A dual role for autophagy in a murine model of lung cancer.

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Journal:  Nat Commun       Date:  2014       Impact factor: 14.919

3.  Orchestration and Prognostic Significance of Immune Checkpoints in the Microenvironment of Primary and Metastatic Renal Cell Cancer.

Authors:  Nicolas A Giraldo; Etienne Becht; Franck Pagès; Georgios Skliris; Virginie Verkarre; Yann Vano; Arnaud Mejean; Nicolas Saint-Aubert; Laetitia Lacroix; Ivo Natario; Audrey Lupo; Marco Alifano; Diane Damotte; Aurelie Cazes; Frederic Triebel; Gordon J Freeman; Marie-Caroline Dieu-Nosjean; Stephane Oudard; Wolf H Fridman; Catherine Sautès-Fridman
Journal:  Clin Cancer Res       Date:  2015-02-16       Impact factor: 12.531

4.  An immunosurveillance mechanism controls cancer cell ploidy.

Authors:  Laura Senovilla; Ilio Vitale; Isabelle Martins; Maximilien Tailler; Claire Pailleret; Mickaël Michaud; Lorenzo Galluzzi; Sandy Adjemian; Oliver Kepp; Mireia Niso-Santano; Shensi Shen; Guillermo Mariño; Alfredo Criollo; Alice Boilève; Bastien Job; Sylvain Ladoire; François Ghiringhelli; Antonella Sistigu; Takahiro Yamazaki; Santiago Rello-Varona; Clara Locher; Vichnou Poirier-Colame; Monique Talbot; Alexander Valent; Francesco Berardinelli; Antonio Antoccia; Fabiola Ciccosanti; Gian Maria Fimia; Mauro Piacentini; Antonio Fueyo; Nicole L Messina; Ming Li; Christopher J Chan; Verena Sigl; Guillaume Pourcher; Christoph Ruckenstuhl; Didac Carmona-Gutierrez; Vladimir Lazar; Josef M Penninger; Frank Madeo; Carlos López-Otín; Mark J Smyth; Laurence Zitvogel; Maria Castedo; Guido Kroemer
Journal:  Science       Date:  2012-09-28       Impact factor: 47.728

Review 5.  Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance.

Authors:  Laurence Zitvogel; Lorenzo Galluzzi; Mark J Smyth; Guido Kroemer
Journal:  Immunity       Date:  2013-07-25       Impact factor: 31.745

Review 6.  Consensus guidelines for the detection of immunogenic cell death.

Authors:  Oliver Kepp; Laura Senovilla; Ilio Vitale; Erika Vacchelli; Sandy Adjemian; Patrizia Agostinis; Lionel Apetoh; Fernando Aranda; Vincenzo Barnaba; Norma Bloy; Laura Bracci; Karine Breckpot; David Brough; Aitziber Buqué; Maria G Castro; Mara Cirone; Maria I Colombo; Isabelle Cremer; Sandra Demaria; Luciana Dini; Aristides G Eliopoulos; Alberto Faggioni; Silvia C Formenti; Jitka Fučíková; Lucia Gabriele; Udo S Gaipl; Jérôme Galon; Abhishek Garg; François Ghiringhelli; Nathalia A Giese; Zong Sheng Guo; Akseli Hemminki; Martin Herrmann; James W Hodge; Stefan Holdenrieder; Jamie Honeychurch; Hong-Min Hu; Xing Huang; Tim M Illidge; Koji Kono; Mladen Korbelik; Dmitri V Krysko; Sherene Loi; Pedro R Lowenstein; Enrico Lugli; Yuting Ma; Frank Madeo; Angelo A Manfredi; Isabelle Martins; Domenico Mavilio; Laurie Menger; Nicolò Merendino; Michael Michaud; Gregoire Mignot; Karen L Mossman; Gabriele Multhoff; Rudolf Oehler; Fabio Palombo; Theocharis Panaretakis; Jonathan Pol; Enrico Proietti; Jean-Ehrland Ricci; Chiara Riganti; Patrizia Rovere-Querini; Anna Rubartelli; Antonella Sistigu; Mark J Smyth; Juergen Sonnemann; Radek Spisek; John Stagg; Abdul Qader Sukkurwala; Eric Tartour; Andrew Thorburn; Stephen H Thorne; Peter Vandenabeele; Francesca Velotti; Samuel T Workenhe; Haining Yang; Wei-Xing Zong; Laurence Zitvogel; Guido Kroemer; Lorenzo Galluzzi
Journal:  Oncoimmunology       Date:  2014-12-13       Impact factor: 8.110

7.  Meta-analysis of organ-specific differences in the structure of the immune infiltrate in major malignancies.

Authors:  Gautier Stoll; Gabriela Bindea; Bernhard Mlecnik; Jérôme Galon; Laurence Zitvogel; Guido Kroemer
Journal:  Oncotarget       Date:  2015-05-20

8.  Screening of novel immunogenic cell death inducers within the NCI Mechanistic Diversity Set.

Authors:  Abdul Qader Sukkurwala; Sandy Adjemian; Laura Senovilla; Mickaël Michaud; Sabrina Spaggiari; Erika Vacchelli; Elisa Elena Baracco; Lorenzo Galluzzi; Laurence Zitvogel; Oliver Kepp; Guido Kroemer
Journal:  Oncoimmunology       Date:  2014-04-16       Impact factor: 8.110

9.  Negative prognostic impact of regulatory T cell infiltration in surgically resected esophageal cancer post-radiochemotherapy.

Authors:  Erika Vacchelli; Michaela Semeraro; David P Enot; Kariman Chaba; Vichnou Poirier Colame; Peggy Dartigues; Aurelie Perier; Irene Villa; Sylvie Rusakiewicz; Caroline Gronnier; Diane Goéré; Christophe Mariette; Laurence Zitvogel; Guido Kroemer
Journal:  Oncotarget       Date:  2015-08-28
  9 in total
  8 in total

1.  The ratio of CD8+/FOXP3 T lymphocytes infiltrating breast tissues predicts the relapse of ductal carcinoma in situ.

Authors:  Michaela Semeraro; Julien Adam; Gautier Stoll; Emilie Louvet; Kariman Chaba; Vichnou Poirier-Colame; Allan Sauvat; Laura Senovilla; Erika Vacchelli; Norma Bloy; Juliette Humeau; Aitziber Buque; Oliver Kepp; Laurence Zitvogel; Fabrice André; Marie-Christine Mathieu; Suzette Delaloge; Guido Kroemer
Journal:  Oncoimmunology       Date:  2016-08-18       Impact factor: 8.110

2.  IL-33 in the tumor microenvironment is associated with the accumulation of FoxP3-positive regulatory T cells in human esophageal carcinomas.

Authors:  Guanglin Cui; Zhenfeng Li; Jingli Ren; Aping Yuan
Journal:  Virchows Arch       Date:  2019-05-06       Impact factor: 4.064

3.  Role of FoxP3-positive regulatory T-cells in regressive and progressive cervical dysplasia.

Authors:  Linda Hertlein; Thomas Kolben; Aurelia Vattai; Nadine Kremer; Sarah Meister; Susanne Beyer; Lucia Keilmann; Anna Hester; Mina Temelkov; Helene Heidegger; Elisa Schmoeckel; Mirjana Kessler; Sven Mahner; Udo Jeschke
Journal:  J Cancer Res Clin Oncol       Date:  2021-11-05       Impact factor: 4.553

4.  A Promising Esophageal Cancer Prognostic Signature of Ferroptosis-Related LncRNA to Predict Immune Scenery and Immunotherapy Response.

Authors:  Xiaoxiao Liu; Xiaobo Shi; Wei Guo; Yue Ke; Yuxing Li; Shupei Pan; Xiaona Li; Mei Liu; Mingzhu Liu; Yuchen Wang; Qinli Ruan; Hongbing Ma
Journal:  Int J Gen Med       Date:  2021-09-18

5.  Comprehensive Analysis of Tumor-Infiltrating Immune Cells and Relevant Therapeutic Strategy in Esophageal Cancer.

Authors:  Guangrong Lu; Liping Chen; Shengjie Wu; Yuao Feng; Tiesu Lin
Journal:  Dis Markers       Date:  2020-05-11       Impact factor: 3.434

6.  A loss-of-function polymorphism in ATG16L1 compromises therapeutic outcome in head and neck carcinoma patients.

Authors:  Julie Le Naour; Zsofia Sztupinszki; Vincent Carbonnier; Odile Casiraghi; Virginie Marty; Lorenzo Galluzzi; Zoltan Szallasi; Guido Kroemer; Erika Vacchelli
Journal:  Oncoimmunology       Date:  2022-04-17       Impact factor: 7.723

Review 7.  Trial watch: IDO inhibitors in cancer therapy.

Authors:  Julie Le Naour; Lorenzo Galluzzi; Laurence Zitvogel; Guido Kroemer; Erika Vacchelli
Journal:  Oncoimmunology       Date:  2020-06-14       Impact factor: 8.110

8.  Impacts of Cigarette Smoking on the Tumor Immune Microenvironment in Esophageal Squamous Cell Carcinoma.

Authors:  Geng Wang; Chuqing Pan; Kexin Cao; Jingbing Zhang; Hui Geng; Kusheng Wu; Jing Wen; Caixia Liu
Journal:  J Cancer       Date:  2022-01-01       Impact factor: 4.207
  8 in total

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