Arup Ratan Choudhury1, Kamrun Nahar Choudhury1, Sheikh Mohammed Shariful Islam1. 1. 1 Bangladesh Institute of Research and Rehabilitation in Diabetes Endocrine and Metabolic Disorders (BIRDEM), Shahbagh, Dhaka, Bangladesh ; 2 National Centre for Control of Rheumatic Fever and Heart Disease, Dhaka, Bangladesh ; 3 Center for Control of Chronic Diseases (CCCD), International Center for Diarrheal Disease Research, Bangladesh, Dhaka, Bangladesh ; 4 Center for International Health (CIH), Ludwig-Maximilians-Universität (LMU), Munich, Germany.
Abstract
BACKGROUND: Evidence suggests that dental diseases might have a role in the development and progression of coronary artery diseases (CAD) and diabetes mellitus (DM). The objective of this study was to determine the relationship of dental diseases with CAD and DM in Bangladesh. METHODS: We conducted a cross-sectional study among 216 consecutive patients admitted in a tertiary hospital between March and July 2011. Data were collected on socio-demographic status, smoking, blood pressure (BP), diet, physical activities, and biochemical measurements of lipid profile, glycated hemoglobin (HbA1c), C-reactive protein (CRP), fibrinogen, creatinine kinase MB (CK-MB), troponin, serum creatinine and serum glutamic-pyruvic transaminase (SGPT). CAD was detected using echocardiographic and coronary angiogram (CAG) reports. All patients underwent oral examination for dental disease. Relationship between dental disease with CAD and DM were explored statistically. RESULTS: The mean age of the participants was 57.8±12.5 years and almost two-thirds (67.1%) were male. A great majority of the patients had CAD (90.3%) and type 2 DM (83.8%), and only 44% suffered from dental diseases. Less than one-third patients presented with acute myocardial infarction (MI), 23% with old MI, 11% unstable angina (UA) and 26.4% with non-ST elevation MI. Logistic regression results indicated that patients with DM and CAD had approximately 2.6 and 4.6 times more odds of association with dental diseases than those without DM and CAD (both P value <0.001). CONCLUSIONS: This study suggests a relationship of dental diseases with CAD and DM among Bangladeshi patients. Further studies are required to confirm these relationships in large clinical studies. Screening for CAD and DM should be considered among those with dental diseases and vice-versa.
BACKGROUND: Evidence suggests that dental diseases might have a role in the development and progression of coronary artery diseases (CAD) and diabetes mellitus (DM). The objective of this study was to determine the relationship of dental diseases with CAD and DM in Bangladesh. METHODS: We conducted a cross-sectional study among 216 consecutive patients admitted in a tertiary hospital between March and July 2011. Data were collected on socio-demographic status, smoking, blood pressure (BP), diet, physical activities, and biochemical measurements of lipid profile, glycated hemoglobin (HbA1c), C-reactive protein (CRP), fibrinogen, creatinine kinase MB (CK-MB), troponin, serum creatinine and serum glutamic-pyruvic transaminase (SGPT). CAD was detected using echocardiographic and coronary angiogram (CAG) reports. All patients underwent oral examination for dental disease. Relationship between dental disease with CAD and DM were explored statistically. RESULTS: The mean age of the participants was 57.8±12.5 years and almost two-thirds (67.1%) were male. A great majority of the patients had CAD (90.3%) and type 2 DM (83.8%), and only 44% suffered from dental diseases. Less than one-third patients presented with acute myocardial infarction (MI), 23% with old MI, 11% unstable angina (UA) and 26.4% with non-ST elevation MI. Logistic regression results indicated that patients with DM and CAD had approximately 2.6 and 4.6 times more odds of association with dental diseases than those without DM and CAD (both P value <0.001). CONCLUSIONS: This study suggests a relationship of dental diseases with CAD and DM among Bangladeshi patients. Further studies are required to confirm these relationships in large clinical studies. Screening for CAD and DM should be considered among those with dental diseases and vice-versa.
Authors: Sheikh Mohammed Shariful Islam; Dewan S Alam; Mohammed Wahiduzzaman; Louis W Niessen; Guenter Froeschl; Uta Ferrari; Jochen Seissler; H M A Rouf; Andreas Lechner Journal: Diabetes Metab Syndr Date: 2014-10-13
Authors: K J Mattila; M S Nieminen; V V Valtonen; V P Rasi; Y A Kesäniemi; S L Syrjälä; P S Jungell; M Isoluoma; K Hietaniemi; M J Jokinen Journal: BMJ Date: 1989-03-25
Authors: Sheikh Mohammed Shariful Islam; Andreas Lechner; Uta Ferrari; Guenter Froeschl; Louis W Niessen; Jochen Seissler; Dewan Shamsul Alam Journal: BMC Public Health Date: 2013-12-21 Impact factor: 3.295
Authors: Kamrun Nahar Choudhury; A K M Mainuddin; Mohammad Wahiduzzaman; Sheikh Mohammed Shariful Islam Journal: Vasc Health Risk Manag Date: 2014-06-30