Omar Ali Abouazza1, Finbarr Condon2, Ailish Hannigan3, Colum Dunne3. 1. University College Hospital Limerick (UCHL), Ireland; Centre for Active Management of Lifelong Ageing (CAMLA), Graduate Entry Medical School (GEMS), University of Limerick, Ireland. 2. University College Hospital Limerick (UCHL), Ireland. 3. Centre for Active Management of Lifelong Ageing (CAMLA), Graduate Entry Medical School (GEMS), University of Limerick, Ireland.
Abstract
AIMS: To develop a Glass Polyalkenoate Cement that is suitable for vertebroplasty. METHODS: Testing was carried out to assess the effect of gamma irradiation used for sterilisation, on the glass transition temperature as well as its mechanical properties, including compressive strength and biflexural strength in vivo as well as testing GPC and PMMA cements post injection in cadaveric human vertebral bone. RESULTS: There was a trend to a higher failure load required for the GPC cement group compared to the current standard PMMA injected group but this was not statistically significant with this small sample size. CONCLUSION: The results are encouraging for future research to continue on GPC cements for use in vertebroplasty.
AIMS: To develop a Glass Polyalkenoate Cement that is suitable for vertebroplasty. METHODS: Testing was carried out to assess the effect of gamma irradiation used for sterilisation, on the glass transition temperature as well as its mechanical properties, including compressive strength and biflexural strength in vivo as well as testing GPC and PMMA cements post injection in cadaveric human vertebral bone. RESULTS: There was a trend to a higher failure load required for the GPC cement group compared to the current standard PMMA injected group but this was not statistically significant with this small sample size. CONCLUSION: The results are encouraging for future research to continue on GPC cements for use in vertebroplasty.
Authors: David F Kallmes; Bryan A Comstock; Patrick J Heagerty; Judith A Turner; David J Wilson; Terry H Diamond; Richard Edwards; Leigh A Gray; Lydia Stout; Sara Owen; William Hollingworth; Basavaraj Ghdoke; Deborah J Annesley-Williams; Stuart H Ralston; Jeffrey G Jarvik Journal: N Engl J Med Date: 2009-08-06 Impact factor: 91.245
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