Literature DB >> 27051470

A fluid collection system for dermal wounds in clinical investigations.

Michael Klopfer1, Derek Banyard, G-P Li1, Alan Widgerow, Mark Bachman1.   

Abstract

In this work, we demonstrate the use of a thin, self adherent, and clinically durable patch device that can collect fluid from a wound site for analysis. This device is manufactured from laminated silicone layers using a novel all-silicone double-molding process. In vitro studies for flow and delivery were followed by a clinical demonstration for exudate collection efficiency from a clinically presented partial thickness burn. The demonstrated utility of this device lends itself for use as a research implement used to clinically sample wound exudate for analysis. This device can serve as a platform for future integration of wearable technology into wound monitoring and care. The demonstrated fabrication method can be used for devices requiring thin membrane construction.

Entities:  

Year:  2016        PMID: 27051470      PMCID: PMC4808064          DOI: 10.1063/1.4943133

Source DB:  PubMed          Journal:  Biomicrofluidics        ISSN: 1932-1058            Impact factor:   2.800


  22 in total

Review 1.  Fabrication of microfluidic systems in poly(dimethylsiloxane).

Authors:  J C McDonald; D C Duffy; J R Anderson; D T Chiu; H Wu; O J Schueller; G M Whitesides
Journal:  Electrophoresis       Date:  2000-01       Impact factor: 3.535

2.  PDMS bonding by means of a portable, low-cost corona system.

Authors:  Kathryn Haubert; Tracy Drier; David Beebe
Journal:  Lab Chip       Date:  2006-10-19       Impact factor: 6.799

3.  Cell handling using microstructured membranes.

Authors:  Daniel Irimia; Mehmet Toner
Journal:  Lab Chip       Date:  2006-02-08       Impact factor: 6.799

4.  Microfluidic dielectrophoretic sorter using gel vertical electrodes.

Authors:  Jason Luo; Edward L Nelson; G P Li; Mark Bachman
Journal:  Biomicrofluidics       Date:  2014-05-23       Impact factor: 2.800

5.  A simple method for fabricating multi-layer PDMS structures for 3D microfluidic chips.

Authors:  Mengying Zhang; Jinbo Wu; Limu Wang; Kang Xiao; Weijia Wen
Journal:  Lab Chip       Date:  2010-02-09       Impact factor: 6.799

6.  Comparative study of cytokine content in the plasma and wound exudate from children with severe burns.

Authors:  E V Mikhal'chik; J A Piterskaya; L Y Budkevich; L Yu Pen'kov; A Facchiano; C De Luca; G A Ibragimova; L G Korkina
Journal:  Bull Exp Biol Med       Date:  2009-11       Impact factor: 0.804

7.  Characterization of polydimethylsiloxane (PDMS) properties for biomedical micro/nanosystems.

Authors:  Alvaro Mata; Aaron J Fleischman; Shuvo Roy
Journal:  Biomed Microdevices       Date:  2005-12       Impact factor: 2.838

8.  A study of cytokines in burn blister fluid related to wound healing.

Authors:  I Ono; H Gunji; J Z Zhang; K Maruyama; F Kaneko
Journal:  Burns       Date:  1995-08       Impact factor: 2.744

9.  Perforated membrane method for fabricating three-dimensional polydimethylsiloxane microfluidic devices.

Authors:  Yiqi Luo; Richard N Zare
Journal:  Lab Chip       Date:  2008-08-19       Impact factor: 6.799

10.  Thin PDMS films using long spin times or tert-butyl alcohol as a solvent.

Authors:  John H Koschwanez; Robert H Carlson; Deirdre R Meldrum
Journal:  PLoS One       Date:  2009-02-24       Impact factor: 3.240

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  1 in total

1.  Topical Negative Pressure on Burns: An Innovative Method for Wound Exudate Collection.

Authors:  Julien Baudoin; Paris Jafari; Joachim Meuli; Lee Ann Applegate; Wassim Raffoul
Journal:  Plast Reconstr Surg Glob Open       Date:  2016-11-10
  1 in total

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