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Literature DB >> 27047952

Getting to the core of fibrosis: targeting redox imbalance in aging.

Louise Hecker¹, Victor J Thannickal¹.

Abstract

Entities: Disease

Year: 2016 PMID： 27047952 PMCID： PMC4791330 DOI： 10.21037/atm.2015.12.45

Source DB: PubMed Journal: Ann Transl Med ISSN： 2305-5839

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44 in total

1. Idiopathic pulmonary fibrosis: a disorder of lung regeneration?

Authors: Victor J Thannickal; James E Loyd
Journal: Am J Respir Crit Care Med Date: 2008-10-01 Impact factor: 21.405

2. Incidence and prevalence of idiopathic pulmonary fibrosis.

Authors: Ganesh Raghu; Derek Weycker; John Edelsberg; Williamson Z Bradford; Gerry Oster
Journal: Am J Respir Crit Care Med Date: 2006-06-29 Impact factor: 21.405

3. Aging, antagonistic pleiotropy and fibrotic disease.

Authors: Victor J Thannickal
Journal: Int J Biochem Cell Biol Date: 2010-06-04 Impact factor: 5.085

Review 4. Reactive oxygen species in cell signaling.

Authors: V J Thannickal; B L Fanburg
Journal: Am J Physiol Lung Cell Mol Physiol Date: 2000-12 Impact factor: 5.464

5. NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart.

Authors: Junya Kuroda; Tetsuro Ago; Shouji Matsushima; Peiyong Zhai; Michael D Schneider; Junichi Sadoshima
Journal: Proc Natl Acad Sci U S A Date: 2010-08-16 Impact factor: 11.205

6. Oxidative stress in lung epithelial cells from patients with idiopathic interstitial pneumonias.

Authors: K Kuwano; N Nakashima; I Inoshima; N Hagimoto; M Fujita; M Yoshimi; T Maeyama; N Hamada; K Watanabe; N Hara
Journal: Eur Respir J Date: 2003-02 Impact factor: 16.671

7. Clinical predictors of a diagnosis of idiopathic pulmonary fibrosis.

Authors: Charlene D Fell; Fernando J Martinez; Lyrica X Liu; Susan Murray; Meilan K Han; Ella A Kazerooni; Barry H Gross; Jeffrey Myers; William D Travis; Thomas V Colby; Galen B Toews; Kevin R Flaherty
Journal: Am J Respir Crit Care Med Date: 2010-01-07 Impact factor: 21.405

8. The oxidative stress theory of aging: embattled or invincible? Insights from non-traditional model organisms.

Authors: Rochelle Buffenstein; Yael H Edrey; Ting Yang; James Mele
Journal: Age (Dordr) Date: 2008-06-14

9. A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis.

Authors: Talmadge E King; Williamson Z Bradford; Socorro Castro-Bernardini; Elizabeth A Fagan; Ian Glaspole; Marilyn K Glassberg; Eduard Gorina; Peter M Hopkins; David Kardatzke; Lisa Lancaster; David J Lederer; Steven D Nathan; Carlos A Pereira; Steven A Sahn; Robert Sussman; Jeffrey J Swigris; Paul W Noble
Journal: N Engl J Med Date: 2014-05-18 Impact factor: 91.245

Getting to the core of fibrosis: targeting redox imbalance in aging.

1. Idiopathic pulmonary fibrosis: a disorder of lung regeneration?

2. Incidence and prevalence of idiopathic pulmonary fibrosis.

3. Aging, antagonistic pleiotropy and fibrotic disease.

Review 4. Reactive oxygen species in cell signaling.

5. NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart.

6. Oxidative stress in lung epithelial cells from patients with idiopathic interstitial pneumonias.

7. Clinical predictors of a diagnosis of idiopathic pulmonary fibrosis.

8. The oxidative stress theory of aging: embattled or invincible? Insights from non-traditional model organisms.

9. A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis.

10. NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development.

Review 1. A Tale of Two Concepts: Harmonizing the Free Radical and Antagonistic Pleiotropy Theories of Aging.

2. Quantitative interaction analysis permits molecular insights into functional NOX4 NADPH oxidase heterodimer assembly.

Review 3. TGF-β1 Signaling and Tissue Fibrosis.

Review 4. Redox mechanisms in age-related lung fibrosis.

5. Bromodomain and Extraterminal (BET) Protein Inhibition Restores Redox Balance and Inhibits Myofibroblast Activation.