Literature DB >> 27047222

Improving the accuracy of wide resection of bone tumors and enhancing implant fit: A cadaveric study.

Carlos G Helguero1, Imin Kao1, David E Komatsu2, Shazad Shaikh2, Derek Hansen2, Jacob Franco3, Fazel Khan2.   

Abstract

BACKGROUND/AIMS: Customized three-dimensional (3-D) jigs have been shown to increase the accuracy of skeletal tumor resection in comparison to freehand techniques. However, the utility of these jigs in subsequently enhancing the fit of endoprosthetic implants has yet to be determined. We hypothesized that custom jigs would improve implant fit compared to freehand resection.
METHODS: Nine matched pairs of cadaveric femurs were scanned by CT. The images then had 'virtual' tumors positioned on the distal medial femoral condyle and preoperative resection plans were generated. Custom implants were designed to fit into the resected spaces and 3-D printed. Similarly, customized 3-D jigs were designed and printed for half of the femurs. Resections were then performed using the jigs or freehand. The implants were positioned in the resected femurs and the accuracy-of-fit was quantitatively assessed by re-scanning the resected femurs and calculating the deviation from the implant (in degrees) for each of the 3 cutting planes. The results were then compared between jig and freehand resections.
RESULTS: For the first plane, the jig resulted in less deviation than the freehand cut, but it did not achieve statistical significance. However, for the 2nd and 3rd planes, the jigs deviated 1.78° and 2.20° from the implants compared to 4.41° and 7.96° for the freehand cuts, both of which were statistically significant improvements (p = 0.038 and p = 0.003).
CONCLUSION: In summary, customized 3-D jigs were shown to improve the accuracy-of-fit between implants and host bone, moving this technology closer to clinical implementation.

Entities:  

Keywords:  3-D printing; Cadaver; Cutting guide; Tumor

Year:  2015        PMID: 27047222      PMCID: PMC4796577          DOI: 10.1016/j.jor.2015.10.010

Source DB:  PubMed          Journal:  J Orthop        ISSN: 0972-978X


  9 in total

1.  Limb salvage with tumor endoprostheses for malignant tumors of the knee.

Authors:  W Plötz; H Rechl; R Burgkart; C Messmer; R Schelter; E Hipp; R Gradinger
Journal:  Clin Orthop Relat Res       Date:  2002-12       Impact factor: 4.176

2.  Endoprosthetic replacement of the distal femur for bone tumours: long-term results.

Authors:  G J C Myers; A T Abudu; S R Carter; R M Tillman; R J Grimer
Journal:  J Bone Joint Surg Br       Date:  2007-04

3.  Patient-specific approach in total knee arthroplasty.

Authors:  Adolph V Lombardi; Keith R Berend; Joanne B Adams
Journal:  Orthopedics       Date:  2008-09       Impact factor: 1.390

4.  Surgical technique: Computer-generated custom jigs improve accuracy of wide resection of bone tumors.

Authors:  Fazel A Khan; Joseph D Lipman; Andrew D Pearle; Patrick J Boland; John H Healey
Journal:  Clin Orthop Relat Res       Date:  2013-01-05       Impact factor: 4.176

5.  Unicompartmental knee arthroplasty with use of novel patient-specific resurfacing implants and personalized jigs.

Authors:  Wolfgang Fitz
Journal:  J Bone Joint Surg Am       Date:  2009-02       Impact factor: 5.284

6.  Limb salvage compared with amputation for osteosarcoma of the distal end of the femur. A long-term oncological, functional, and quality-of-life study.

Authors:  B T Rougraff; M A Simon; J S Kneisl; D B Greenberg; H J Mankin
Journal:  J Bone Joint Surg Am       Date:  1994-05       Impact factor: 5.284

7.  Feasibility of limb salvage and survival in soft tissue sarcomas.

Authors:  C P Karakousis; L J Emrich; U Rao; R M Krishnamsetty
Journal:  Cancer       Date:  1986-02-01       Impact factor: 6.860

8.  Long-term results of allograft replacement in the management of bone tumors.

Authors:  H J Mankin; M C Gebhardt; L C Jennings; D S Springfield; W W Tomford
Journal:  Clin Orthop Relat Res       Date:  1996-03       Impact factor: 4.176

9.  A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system.

Authors:  W F Enneking; W Dunham; M C Gebhardt; M Malawar; D J Pritchard
Journal:  Clin Orthop Relat Res       Date:  1993-01       Impact factor: 4.176

  9 in total
  2 in total

1.  A novel intraoperative method to project osteotomy lines for accurate resection of primary bone sarcomas.

Authors:  Guangyu He; Amos Z Dai; Vamiq M Mustahsan; Aadit T Shah; Liming Li; Jafar A Khan; Michael R Bielski; David E Komatsu; Imin Kao; Fazel A Khan
Journal:  J Orthop       Date:  2022-05-11

Review 2.  Anatomical Engineering and 3D Printing for Surgery and Medical Devices: International Review and Future Exponential Innovations.

Authors:  José Cornejo; Jorge A Cornejo-Aguilar; Mariela Vargas; Carlos G Helguero; Rafhael Milanezi de Andrade; Sebastian Torres-Montoya; Javier Asensio-Salazar; Alvaro Rivero Calle; Jaime Martínez Santos; Aaron Damon; Alfredo Quiñones-Hinojosa; Miguel D Quintero-Consuegra; Juan Pablo Umaña; Sebastian Gallo-Bernal; Manolo Briceño; Paolo Tripodi; Raul Sebastian; Paul Perales-Villarroel; Gabriel De la Cruz-Ku; Travis Mckenzie; Victor Sebastian Arruarana; Jiakai Ji; Laura Zuluaga; Daniela A Haehn; Albit Paoli; Jordan C Villa; Roxana Martinez; Cristians Gonzalez; Rafael J Grossmann; Gabriel Escalona; Ilaria Cinelli; Thais Russomano
Journal:  Biomed Res Int       Date:  2022-03-24       Impact factor: 3.411

  2 in total

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