Literature DB >> 27045137

Endothelial-to-Mesenchymal Transition: An Evolving Paradigm and a Promising Therapeutic Target in PAH.

Kurt R Stenmark1, Maria Frid2, Frédéric Perros2.   

Abstract

Entities:  

Keywords:  Editorials; cell differentiation; endothelial cells; endothelial dysfunction; hypertension, pulmonary; smooth muscle, inflammation

Mesh：

Substances：

Year:  2016        PMID： 27045137      PMCID： PMC4866805          DOI： 10.1161/CIRCULATIONAHA.116.022479

Source DB:  PubMed          Journal:  Circulation        ISSN： 0009-7322            Impact factor:   29.690


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  19 in total

Review 1.  Perspectives on endothelial-to-mesenchymal transition: potential contribution to vascular remodeling in chronic pulmonary hypertension.

Authors:  Enrique Arciniegas; Maria G Frid; Ivor S Douglas; Kurt R Stenmark
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2007-03-23       Impact factor: 5.464

Review 2.  Epithelial-mesenchymal transitions in development and disease.

Authors:  Jean Paul Thiery; Hervé Acloque; Ruby Y J Huang; M Angela Nieto
Journal:  Cell       Date:  2009-11-25       Impact factor: 41.582

3.  Oxidative stress mediates the conversion of endothelial cells into myofibroblasts via a TGF-β1 and TGF-β2-dependent pathway.

Authors:  Ignacio Montorfano; Alvaro Becerra; Roberto Cerro; César Echeverría; Elizabeth Sáez; María Gabriela Morales; Ricardo Fernández; Claudio Cabello-Verrugio; Felipe Simon
Journal:  Lab Invest       Date:  2014-07-28       Impact factor: 5.662

4.  Endothelial to Mesenchymal Transition Contributes to Endothelial Dysfunction in Pulmonary Arterial Hypertension.

Authors:  Robert B Good; Adrian J Gilbane; Sarah L Trinder; Christopher P Denton; Gerry Coghlan; David J Abraham; Alan M Holmes
Journal:  Am J Pathol       Date:  2015-05-05       Impact factor: 4.307

5.  Targeted gene delivery of BMPR2 attenuates pulmonary hypertension.

Authors:  A M Reynolds; M D Holmes; S M Danilov; P N Reynolds
Journal:  Eur Respir J       Date:  2011-07-07       Impact factor: 16.671

6.  Plexiform lesions in pulmonary arterial hypertension composition, architecture, and microenvironment.

Authors:  Danny Jonigk; Heiko Golpon; Clemens L Bockmeyer; Lavinia Maegel; Marius M Hoeper; Jens Gottlieb; Nils Nickel; Kais Hussein; Ulrich Maus; Ulrich Lehmann; Sabina Janciauskiene; Tobias Welte; Axel Haverich; Johanna Rische; Hans Kreipe; Florian Laenger
Journal:  Am J Pathol       Date:  2011-05-11       Impact factor: 4.307

Review 7.  Molecular mechanisms of epithelial-mesenchymal transition.

Authors:  Samy Lamouille; Jian Xu; Rik Derynck
Journal:  Nat Rev Mol Cell Biol       Date:  2014-03       Impact factor: 94.444

8.  Inhibition of nuclear factor-κB in the lungs prevents monocrotaline-induced pulmonary hypertension in mice.

Authors:  Li Li; Chuanyu Wei; Il-Kwon Kim; Yvonne Janssen-Heininger; Sudhiranjan Gupta
Journal:  Hypertension       Date:  2014-03-10       Impact factor: 10.190

9.  Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor.

Authors:  Carl Atkinson; Susan Stewart; Paul D Upton; Rajiv Machado; Jennifer R Thomson; Richard C Trembath; Nicholas W Morrell
Journal:  Circulation       Date:  2002-04-09       Impact factor: 29.690

Review 10.  Controlling the angiogenic switch: a balance between two distinct TGF-b receptor signaling pathways.

Authors:  Marie-Jose Goumans; Franck Lebrin; Gudrun Valdimarsdottir
Journal:  Trends Cardiovasc Med       Date:  2003-10       Impact factor: 6.677
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  37 in total

1.  The Roles of Immunity in the Prevention and Evolution of Pulmonary Arterial Hypertension.

Authors:  Mark R Nicolls; Norbert F Voelkel
Journal:  Am J Respir Crit Care Med       Date:  2017-05-15       Impact factor: 21.405

2.  A Metabolic Basis for Endothelial-to-Mesenchymal Transition.

Authors:  Jianhua Xiong; Hiroyuki Kawagishi; Ye Yan; Jie Liu; Quinn S Wells; Lia R Edmunds; Maria M Fergusson; Zu-Xi Yu; Ilsa I Rovira; Evan L Brittain; Michael J Wolfgang; Michael J Jurczak; Joshua P Fessel; Toren Finkel
Journal:  Mol Cell       Date:  2018-02-08       Impact factor: 17.970

Review 3.  Translating Research into Improved Patient Care in Pulmonary Arterial Hypertension.

Authors:  Sébastien Bonnet; Steeve Provencher; Christophe Guignabert; Frédéric Perros; Olivier Boucherat; Ralph Theo Schermuly; Paul M Hassoun; Marlene Rabinovitch; Mark R Nicolls; Marc Humbert
Journal:  Am J Respir Crit Care Med       Date:  2017-03-01       Impact factor: 21.405

Review 4.  Transcription factors, transcriptional coregulators, and epigenetic modulation in the control of pulmonary vascular cell phenotype: therapeutic implications for pulmonary hypertension (2015 Grover Conference series).

Authors:  Soni S Pullamsetti; Frédéric Perros; Prakash Chelladurai; Jason Yuan; Kurt Stenmark
Journal:  Pulm Circ       Date:  2016-12       Impact factor: 3.017

Review 5.  Vascular Cells in Blood Vessel Wall Development and Disease.

Authors:  R Mazurek; J M Dave; R R Chandran; A Misra; A Q Sheikh; D M Greif
Journal:  Adv Pharmacol       Date:  2016-10-14

6.  Endothelial-to-Mesenchymal Transition and Inflammation Play Key Roles in Cyclophilin A-Induced Pulmonary Arterial Hypertension.

Authors:  Chao Xue; Sharon Senchanthisai; Mark Sowden; Jinjiang Pang; Jim White; Bradford C Berk
Journal:  Hypertension       Date:  2020-08-24       Impact factor: 10.190

7.  Isolation and characterization of endothelial-to-mesenchymal transition cells in pulmonary arterial hypertension.

Authors:  Toshio Suzuki; Erica J Carrier; Megha H Talati; Anandharajan Rathinasabapathy; Xinping Chen; Rintaro Nishimura; Yuji Tada; Koichiro Tatsumi; James West
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2017-09-21       Impact factor: 5.464

8.  Transplantation of Mesenchymal Stem Cells Attenuates Pulmonary Hypertension by Normalizing the Endothelial-to-Mesenchymal Transition.

Authors:  Junyi Huang; Wenju Lu; Haiping Ouyang; Yuqin Chen; Chenting Zhang; Xiaoyun Luo; Meichan Li; Jiaze Shu; Qiuyu Zheng; Haixia Chen; Jiyuan Chen; Haiyang Tang; Dejun Sun; Jason X-J Yuan; Kai Yang; Jian Wang
Journal:  Am J Respir Cell Mol Biol       Date:  2020-01       Impact factor: 6.914

Review 9.  Role of extracellular matrix in the pathogenesis of pulmonary arterial hypertension.

Authors:  Thenappan Thenappan; Stephen Y Chan; E Kenneth Weir
Journal:  Am J Physiol Heart Circ Physiol       Date:  2018-08-24       Impact factor: 4.733

Review 10.  Dynamic and diverse changes in the functional properties of vascular smooth muscle cells in pulmonary hypertension.

Authors:  Kurt R Stenmark; Maria G Frid; Brian B Graham; Rubin M Tuder
Journal:  Cardiovasc Res       Date:  2018-03-15       Impact factor: 10.787
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