Literature DB >> 27649290

Translating Research into Improved Patient Care in Pulmonary Arterial Hypertension.

Sébastien Bonnet1,2, Steeve Provencher1,2, Christophe Guignabert3,4, Frédéric Perros3,4, Olivier Boucherat1, Ralph Theo Schermuly5, Paul M Hassoun6, Marlene Rabinovitch7, Mark R Nicolls8,9, Marc Humbert3,4,10.   

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Year:  2017        PMID： 27649290      PMCID： PMC5440916          DOI： 10.1164/rccm.201607-1515PP

Source DB:  PubMed          Journal:  Am J Respir Crit Care Med        ISSN： 1073-449X            Impact factor:   21.405


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  125 in total

1.  A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth.

Authors:  Sébastien Bonnet; Stephen L Archer; Joan Allalunis-Turner; Alois Haromy; Christian Beaulieu; Richard Thompson; Christopher T Lee; Gary D Lopaschuk; Lakshmi Puttagunta; Sandra Bonnet; Gwyneth Harry; Kyoko Hashimoto; Christopher J Porter; Miguel A Andrade; Bernard Thebaud; Evangelos D Michelakis
Journal:  Cancer Cell       Date:  2007-01       Impact factor: 31.743

Review 2.  Chemotherapy-induced pulmonary hypertension: role of alkylating agents.

Authors:  Benoît Ranchoux; Sven Günther; Rozenn Quarck; Marie-Camille Chaumais; Peter Dorfmüller; Fabrice Antigny; Sébastien J Dumas; Nicolas Raymond; Edmund Lau; Laurent Savale; Xavier Jaïs; Olivier Sitbon; Gérald Simonneau; Kurt Stenmark; Sylvia Cohen-Kaminsky; Marc Humbert; David Montani; Frédéric Perros
Journal:  Am J Pathol       Date:  2014-12-11       Impact factor: 4.307

3.  Skeletal muscle proteomic signature and metabolic impairment in pulmonary hypertension.

Authors:  Simon Malenfant; François Potus; Frédéric Fournier; Sandra Breuils-Bonnet; Aude Pflieger; Sylvie Bourassa; Ève Tremblay; Benjamin Nehmé; Arnaud Droit; Sébastien Bonnet; Steeve Provencher
Journal:  J Mol Med (Berl)       Date:  2014-12-30       Impact factor: 4.599

4.  Metabolic Modulation of Clear-cell Renal Cell Carcinoma with Dichloroacetate, an Inhibitor of Pyruvate Dehydrogenase Kinase.

Authors:  Adam Kinnaird; Peter Dromparis; Bruno Saleme; Vikram Gurtu; Kristalee Watson; Roxane Paulin; Sotirios Zervopoulos; Trevor Stenson; Gopinath Sutendra; Desmond B Pink; Katia Carmine-Simmen; Ronald Moore; John D Lewis; Evangelos D Michelakis
Journal:  Eur Urol       Date:  2016-02-18       Impact factor: 20.096

5.  Dexfenfluramine protects against pulmonary hypertension in rats.

Authors:  Yoshihide Mitani; Asuman Mutlu; James C Russell; David N Brindley; John DeAlmeida; Marlene Rabinovitch
Journal:  J Appl Physiol (1985)       Date:  2002-11

6.  Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension.

Authors:  M Sean McMurtry; Stephen L Archer; Dario C Altieri; Sebastien Bonnet; Alois Haromy; Gwyneth Harry; Sandra Bonnet; Lakshmi Puttagunta; Evangelos D Michelakis
Journal:  J Clin Invest       Date:  2005-06       Impact factor: 14.808

7.  Rho-kinase inhibition alleviates pulmonary hypertension in transgenic mice expressing a dominant-negative type II bone morphogenetic protein receptor gene.

Authors:  Tadashi Yasuda; Yuji Tada; Nobuhiro Tanabe; Koichiro Tatsumi; James West
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2011-08-19       Impact factor: 5.464

8.  Overexpression of the serine elastase inhibitor elafin protects transgenic mice from hypoxic pulmonary hypertension.

Authors:  Syed H E Zaidi; Xiao-Mang You; Sorana Ciura; Mansoor Husain; Marlene Rabinovitch
Journal:  Circulation       Date:  2002-01-29       Impact factor: 29.690

9.  Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension.

Authors:  Gopinath Sutendra; Sebastien Bonnet; Gael Rochefort; Alois Haromy; Karalyn D Folmes; Gary D Lopaschuk; Jason R B Dyck; Evangelos D Michelakis
Journal:  Sci Transl Med       Date:  2010-08-11       Impact factor: 17.956

10.  Characterizing the molecular spatial and temporal field of injury in early-stage smoker non-small cell lung cancer patients after definitive surgery by expression profiling.

Authors:  Humam Kadara; Li Shen; Junya Fujimoto; Pierre Saintigny; Chi-Wan Chow; Wenhua Lang; Zuoming Chu; Melinda Garcia; Mohamed Kabbout; You-Hong Fan; Carmen Behrens; Diane A Liu; Li Mao; J Jack Lee; Kathryn A Gold; Jing Wang; Kevin R Coombes; Edward S Kim; Waun Ki Hong; Ignacio I Wistuba
Journal:  Cancer Prev Res (Phila)       Date:  2012-10-19
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  55 in total

1.  Reply: Transforming Growth Factor β1- and Bone Morphogenetic Protein 2/PPARγ-regulated MicroRNAs in Pulmonary Arterial Hypertension.

Authors:  Hyung J Chun; Sebastien Bonnet; Stephen Y Chan
Journal:  Am J Respir Crit Care Med       Date:  2017-11-01       Impact factor: 21.405

2.  The Roles of Immunity in the Prevention and Evolution of Pulmonary Arterial Hypertension.

Authors:  Mark R Nicolls; Norbert F Voelkel
Journal:  Am J Respir Crit Care Med       Date:  2017-05-15       Impact factor: 21.405

Review 3.  Sex, Gender, and Sex Hormones in Pulmonary Hypertension and Right Ventricular Failure.

Authors:  James Hester; Corey Ventetuolo; Tim Lahm
Journal:  Compr Physiol       Date:  2019-12-18       Impact factor: 9.090

4.  Pulmonary vascular mechanical consequences of ischemic heart failure and implications for right ventricular function.

Authors:  Jennifer L Philip; Thomas M Murphy; David A Schreier; Sydney Stevens; Diana M Tabima; Margie Albrecht; Andrea L Frump; Timothy A Hacker; Tim Lahm; Naomi C Chesler
Journal:  Am J Physiol Heart Circ Physiol       Date:  2019-02-15       Impact factor: 4.733

5.  Transcriptomic modifications in developmental cardiopulmonary adaptations to chronic hypoxia using a murine model of simulated high-altitude exposure.

Authors:  Sheila Krishnan; Robert S Stearman; Lily Zeng; Amanda Fisher; Elizabeth A Mickler; Brooke H Rodriguez; Edward R Simpson; Todd Cook; James E Slaven; Mircea Ivan; Mark W Geraci; Tim Lahm; Robert S Tepper
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2020-07-08       Impact factor: 5.464

6.  The cancer hypothesis of pulmonary arterial hypertension: the next ten years.

Authors:  David Condon; Stuti Agarwal; Ananya Chakraborty; Vinicio A de Jesus Perez
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2020-03-18       Impact factor: 5.464

7.  Update in Pulmonary Vascular Disease 2016 and 2017.

Authors:  Evan L Brittain; Thennapan Thennapan; Bradley A Maron; Stephen Y Chan; Eric D Austin; Edda Spiekerkoetter; Harm J Bogaard; Christophe Guignabert; Roxane Paulin; Roberto F Machado; Paul B Yu
Journal:  Am J Respir Crit Care Med       Date:  2018-07-01       Impact factor: 21.405

Review 8.  Emerging role of angiogenesis in adaptive and maladaptive right ventricular remodeling in pulmonary hypertension.

Authors:  Andrea L Frump; Sébastien Bonnet; Vinicio A de Jesus Perez; Tim Lahm
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2017-11-02       Impact factor: 5.464

9.  Accelerometry: Improving Objective Assessments of Therapeutic Impact in Pediatric Pulmonary Arterial Hypertension.

Authors:  Eric D Austin; Jeffrey A Feinstein
Journal:  Am J Respir Crit Care Med       Date:  2017-07-15       Impact factor: 21.405

10.  Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension.

Authors:  Olivier Boucherat; Thibaut Peterlini; Alice Bourgeois; Valérie Nadeau; Sandra Breuils-Bonnet; Stéphanie Boilet-Molez; François Potus; Jolyane Meloche; Sophie Chabot; Caroline Lambert; Eve Tremblay; Young Chan Chae; Dario C Altieri; Gopinath Sutendra; Evangelos D Michelakis; Roxane Paulin; Steeve Provencher; Sébastien Bonnet
Journal:  Am J Respir Crit Care Med       Date:  2018-07-01       Impact factor: 21.405
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