Literature DB >> 27043447

Self-Assembly of the Cyclic Lipopeptide Daptomycin: Spherical Micelle Formation Does Not Depend on the Presence of Calcium Chloride.

Steven Kirkham1, Valeria Castelletto1, Ian William Hamley2, Katsuaki Inoue3, Robert Rambo3, Mehedi Reza4, Janne Ruokolainen4.   

Abstract

The cyclic lipopeptide Daptomycin, used as a treatment for infections where antimicrobial resistance is observed, is shown to self-assemble into spherical micelles above a critical aggregation concentration. Micelles are observed either in the absence or presence of CaCl2 , in contrast to claims in the literature that CaCl2 is required for micellization.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  antimicrobial peptides; lipopeptide; micelles; secondary structure; self-assembly

Mesh：

Substances：

Year:  2016        PMID： 27043447     DOI： 10.1002/cphc.201600308

Source DB:  PubMed          Journal:  Chemphyschem        ISSN： 1439-4235            Impact factor:   3.102


  6 in total

1.  Molecular State of the Membrane-Active Antibiotic Daptomycin.

Authors:  Ming-Tao Lee; Wei-Chin Hung; Meng-Hsuan Hsieh; Hsiung Chen; Yu-Yung Chang; Huey W Huang
Journal:  Biophys J       Date:  2017-07-11       Impact factor: 4.033

2.  Design, Synthesis, and Nanostructure-Dependent Antibacterial Activity of Cationic Peptide Amphiphiles.

Authors:  Nathalia Rodrigues de Almeida; Yuchun Han; Jesus Perez; Sydney Kirkpatrick; Yilin Wang; Martin Conda Sheridan
Journal:  ACS Appl Mater Interfaces       Date:  2019-01-10       Impact factor: 9.229

Review 3.  Peptide hormones and lipopeptides: from self-assembly to therapeutic applications.

Authors:  J A Hutchinson; S Burholt; I W Hamley
Journal:  J Pept Sci       Date:  2017-01-27       Impact factor: 1.905

4.  Physicochemical Characterization of Daptomycin Interaction with Negatively Charged Lipid Membranes.

Authors:  Joanna Juhaniewicz-Dębińska; Damian Dziubak; Sławomir Sęk
Journal:  Langmuir       Date:  2020-05-07       Impact factor: 3.882

5.  High-speed atomic force microscopy highlights new molecular mechanism of daptomycin action.

Authors:  Francesca Zuttion; Adai Colom; Stefan Matile; Denes Farago; Frédérique Pompeo; Janos Kokavecz; Anne Galinier; James Sturgis; Ignacio Casuso
Journal:  Nat Commun       Date:  2020-12-09       Impact factor: 14.919

Review 6.  Insight to Functional Conformation and Noncovalent Interactions of Protein-Protein Assembly Using MALDI Mass Spectrometry.

Authors:  Marco Giampà; Elvira Sgobba
Journal:  Molecules       Date:  2020-10-28       Impact factor: 4.411
  6 in total

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