Literature DB >> 27042485

Automated Triplex (HBV, HCV and HIV) NAT Assay Systems for Blood Screening in India.

Manoj Kumar Rajput1.   

Abstract

This review is confined to triplex nucleic acid testing (NAT) assays to be used on fully automated platform. Around the world, these assays are being used at various transfusion medicine centres or blood banks to screen blood units for HBV, HCV and HIV. These assay systems can screen up to 1000 blood units for HBV, HCV and HIV simultaneously in a day. This area has been dominated by mainly two manufacturers: M/s Gen-Probe-Novartis and M/s Roche Molecular Systems. The triplex NAT assay systems of both manufacturers are licensed by United States Food and Drug Administration. There is not much awareness about the technology and procedures used in these assays. The main objective of this review is to create awareness about the technology and procedure of these assays.

Keywords:  Individual donations; Molecular diagnostics; Transfusion transmitted infections

Year:  2016        PMID: 27042485      PMCID: PMC4800550          DOI: 10.7860/JCDR/2016/16981.7319

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  20 in total

1.  Risk Minimization Measures for Blood Screening HIV-1 Nucleic Acid Amplification Technique Assays in Germany.

Authors:  Michael Chudy; Julia Kress; Jochen Halbauer; Margarethe Heiden; Markus B Funk; C Micha Nübling
Journal:  Transfus Med Hemother       Date:  2013-12-19       Impact factor: 3.747

2.  Blood donation screening for hepatitis B virus markers in the era of nucleic acid testing: are all tests of value?

Authors:  Susan L Stramer; Shimian Zou; Edward P Notari; Gregory A Foster; David E Krysztof; Fatemeh Musavi; Roger Y Dodd
Journal:  Transfusion       Date:  2011-08-02       Impact factor: 3.157

3.  Evaluation of two, commercial, multi-dye, nucleic acid amplification technology tests, for HBV/HCV/HIV-1/HIV-2 and B19V/HAV, for screening blood and plasma for further manufacture.

Authors:  M M Müller; M I G Fraile; M K Hourfar; L B Peris; W Sireis; M G Rubin; E M López; G T Rodriguez; E Seifried; J Saldanha; M Schmidt
Journal:  Vox Sang       Date:  2012-08-01       Impact factor: 2.144

4.  Individual donor nucleic acid testing for blood safety against HIV-1 and hepatitis B and C viruses in a tertiary care hospital.

Authors:  K Chatterjee; P Coshic; M Borgohain; R M Thapliyal; S Chakroborty; S Sunder
Journal:  Natl Med J India       Date:  2012 Jul-Aug       Impact factor: 0.537

5.  Sensitivity of individual-donation and minipool nucleic acid amplification test options in detecting window period and occult hepatitis B virus infections.

Authors:  Marion Vermeulen; Charl Coleman; Josephine Mitchel; Ravi Reddy; Harry van Drimmelen; Tracy Ficket; Nico Lelie
Journal:  Transfusion       Date:  2013-04-29       Impact factor: 3.157

6.  Refinement of a viral transmission risk model for blood donations in seroconversion window phase screened by nucleic acid testing in different pool sizes and repeat test algorithms.

Authors:  Jos Weusten; Marion Vermeulen; Harry van Drimmelen; Nico Lelie
Journal:  Transfusion       Date:  2010-08-12       Impact factor: 3.157

Review 7.  Risks of transfusion-transmitted infections: 2003.

Authors:  Gregory J Pomper; YanYun Wu; Edward L Snyder
Journal:  Curr Opin Hematol       Date:  2003-11       Impact factor: 3.284

8.  Residual infectious disease risk in screened blood transfusion from a high-prevalence population: Santa Catarina, Brazil.

Authors:  Christina Maresch; Philip J Schluter; Andrew D Wilson; Adrian Sleigh
Journal:  Transfusion       Date:  2007-11-13       Impact factor: 3.157

9.  Comparison of two automated nucleic acid testing systems for simultaneous detection of human immunodeficiency virus and hepatitis C virus RNA and hepatitis B virus DNA.

Authors:  Angelo R Margaritis; Stewart M Brown; Clive R Seed; Philip Kiely; Bruno D'Agostino; Anthony J Keller
Journal:  Transfusion       Date:  2007-10       Impact factor: 3.157

10.  First WHO International Reference Panel containing hepatitis B virus genotypes A-G for assays of the viral DNA.

Authors:  M Chudy; K-M Hanschmann; J Kress; S Nick; R Campos; U Wend; W Gerlich; C M Nübling
Journal:  J Clin Virol       Date:  2012-09-12       Impact factor: 3.168

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  1 in total

1.  Self-testing for HIV, HBV, and HCV using finger-stick whole-blood multiplex immunochromatographic rapid test: A pilot feasibility study in sub-Saharan Africa.

Authors:  Serge Tonen-Wolyec; Roland Marini Djang'eing'a; Salomon Batina-Agasa; Charles Kayembe Tshilumba; Jérémie Muwonga Masidi; Marie-Pierre Hayette; Laurent Bélec
Journal:  PLoS One       Date:  2021-04-09       Impact factor: 3.240

  1 in total

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