| Literature DB >> 27040846 |
Marion Sassier1, Bertrand Mennecier2, Anthony Gschwend2, Mikahl Rein3, Antoine Coquerel4, Xavier Humbert5, Joachim Alexandre4, Sophie Fedrizzi4, Radj Gervais6.
Abstract
We report two cases of acute hepatitis induced by crizotinib in patients with ALK-rearranged non-small cell lung cancer (NSCLC) who were treated after by a second generation of ALK inhibitor without any incident. These cases suggest that ceritinib could be used as an alternative agent when crizotinib is responsible for hepatitis.Entities:
Keywords: Anaplastic lymphoma kinase (ALK); Ceritinib; Crizotinib; Hepatitis; Non-small-cell-lung-cancer (NSCLC)
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Year: 2016 PMID: 27040846 DOI: 10.1016/j.lungcan.2016.02.008
Source DB: PubMed Journal: Lung Cancer ISSN: 0169-5002 Impact factor: 5.705