| Literature DB >> 27040493 |
Nico Keller1, Tobias M Nargang1, Matthias Runck1, Frederik Kotz1, Andreas Striegel1, Kai Sachsenheimer1, Denis Klemm1, Kerstin Länge1, Matthias Worgull1, Christiane Richter1, Dorothea Helmer1, Bastian E Rapp1.
Abstract
Cyclic olefin copolymer (COC) is widely used in microfluidics due to its UV-transparency, its biocompatibility and high chemical resistance. Here we present a fast and cost-effective solvent bonding technique, which allows for the efficient bonding of protein-patterned COC structures. The bonding process is carried out at room temperature and takes less than three minutes. Enzyme activity is retained upon bonding and microstructure deformation does not occur.Entities:
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Year: 2016 PMID： 27040493 DOI： 10.1039/c5lc01498k
Source DB: PubMed Journal: Lab Chip ISSN： 1473-0189 Impact factor: 6.799