Takenori Yamauchi1, Shouhei Takeuchi2, Yoichiro Horii3, Yuko Yamano1, Yoshiki Kuroda2, Toshio Nakadate4. 1. Department of Hygiene and Preventive Medicine, School of Medicine, Showa University, Tokyo, 142-8555, Japan. 2. Department of Public Health, Faculty of Medicine, University of Miyazaki, Miyazaki, 889-1692, Japan. 3. Center for Collaborative Research and Community Cooperation, University of Miyazaki, Miyazaki, 889-1692, Japan. 4. Department of Hygiene and Preventive Medicine, School of Medicine, Showa University, Tokyo, 142-8555, Japan. nakadate@med.showa-u.ac.jp.
Abstract
OBJECTIVES: The law in Japan requires the declaration of a state of emergency and implementation of countermeasures for an epidemic of a new infectious disease. However, because a state of emergency has never been declared in Japan, its effects remain unknown. The required countermeasures are similar to those implemented in the foot-and-mouth disease epidemic in Miyazaki in 2010. This study aimed to quantitatively estimate the effect of the declaration in 2010 and investigate the nature of the epidemic based on the day on which the declaration took effect. METHODS: Only publicly available data were used. Data for farms in the most affected town were analyzed. A modified susceptible-infected-recovered model was used to estimate the effect and for the simulation. Another model was used to estimate the effective reproduction number. RESULTS: After the declaration, the intra-bovine transmission rate decreased by 18.1 %, and there were few days when the effective reproduction number was >1.0. A few weeks delay in the declaration significantly increased the possibility of epidemic, number of farms at peak, and final infection scale. CONCLUSIONS: Based on the substantial decrease in the transmission rate after the declaration of a state of emergency in 2010, a future declaration will have a similar effect for a new infectious disease even though a direct extrapolation is not valid. Although a declaration should be carefully considered owing to the potential socioeconomic effects, it is essential to prepare for the implementation given that a delay of only a few weeks should be acceptable.
OBJECTIVES: The law in Japan requires the declaration of a state of emergency and implementation of countermeasures for an epidemic of a new infectious disease. However, because a state of emergency has never been declared in Japan, its effects remain unknown. The required countermeasures are similar to those implemented in the foot-and-mouth disease epidemic in Miyazaki in 2010. This study aimed to quantitatively estimate the effect of the declaration in 2010 and investigate the nature of the epidemic based on the day on which the declaration took effect. METHODS: Only publicly available data were used. Data for farms in the most affected town were analyzed. A modified susceptible-infected-recovered model was used to estimate the effect and for the simulation. Another model was used to estimate the effective reproduction number. RESULTS: After the declaration, the intra-bovine transmission rate decreased by 18.1 %, and there were few days when the effective reproduction number was >1.0. A few weeks delay in the declaration significantly increased the possibility of epidemic, number of farms at peak, and final infection scale. CONCLUSIONS: Based on the substantial decrease in the transmission rate after the declaration of a state of emergency in 2010, a future declaration will have a similar effect for a new infectious disease even though a direct extrapolation is not valid. Although a declaration should be carefully considered owing to the potential socioeconomic effects, it is essential to prepare for the implementation given that a delay of only a few weeks should be acceptable.
Entities:
Keywords:
Declaration of a state of emergency; Effective reproduction number; Foot-and-mouth disease; Mathematical model; New infectious disease
Authors: C Favier; N Degallier; M G Rosa-Freitas; J P Boulanger; J R Costa Lima; J F Luitgards-Moura; C E Menkès; B Mondet; C Oliveira; E T S Weimann; P Tsouris Journal: Trop Med Int Health Date: 2006-03 Impact factor: 2.622