Karn Wijarnpreecha1, Charat Thongprayoon1, Panadeekarn Panjawatanan2, Patompong Ungprasert3,4. 1. Department of Internal Medicine, Bassett Medical Center, Cooperstown, New York, USA. 2. Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. 3. Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA. 4. Division of Rheumatology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Abstract
BACKGROUND AND AIM: Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease worldwide. Several studies have suggested that short sleep duration could be a risk factor for NAFLD. However, results of those reports are inconsistent. This meta-analysis was conducted with an attempt to summarize all available data. METHODS: A comprehensive literature review was performed using MEDLINE and EMBASE database. Studies that reported relative risks, odd ratios or hazard ratios comparing the risk of NAFLD among participants who had short sleep duration versus those with longer sleep duration were included. Pooled risk ratios and 95% confidence interval were calculated using a random-effect, generic inverse variance method. RESULTS: Six studies met the eligibility criteria and were included in the meta-analysis. The risk of NAFLD in participants who had short sleep duration was significantly higher than participants with longer sleep duration with pooled risk ratios of 1.19 (95% confidence interval, 1.04-1.36, I2 = 0%). CONCLUSIONS: Our study demonstrated a small but significantly increased risk of NAFLD among participants who had short sleep duration.
BACKGROUND AND AIM: Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease worldwide. Several studies have suggested that short sleep duration could be a risk factor for NAFLD. However, results of those reports are inconsistent. This meta-analysis was conducted with an attempt to summarize all available data. METHODS: A comprehensive literature review was performed using MEDLINE and EMBASE database. Studies that reported relative risks, odd ratios or hazard ratios comparing the risk of NAFLD among participants who had short sleep duration versus those with longer sleep duration were included. Pooled risk ratios and 95% confidence interval were calculated using a random-effect, generic inverse variance method. RESULTS: Six studies met the eligibility criteria and were included in the meta-analysis. The risk of NAFLD in participants who had short sleep duration was significantly higher than participants with longer sleep duration with pooled risk ratios of 1.19 (95% confidence interval, 1.04-1.36, I2 = 0%). CONCLUSIONS: Our study demonstrated a small but significantly increased risk of NAFLD among participants who had short sleep duration.
Authors: Kathryn E Royse; Hashem B El-Serag; Liang Chen; Donna L White; Lauren Hale; Haleh Sangi-Haghpeykar; Li Jiao Journal: J Womens Health (Larchmt) Date: 2017-09-21 Impact factor: 2.681
Authors: Bertha Araceli Marin-Alejandre; Itziar Abete; Irene Cantero; Jose I Riezu-Boj; Fermín I Milagro; J Ignacio Monreal; Mariana Elorz; José Ignacio Herrero; Alberto Benito-Boillos; Jorge Quiroga; Ana Martinez-Echeverria; Juan Isidro Uriz-Otano; María Pilar Huarte-Muniesa; Josep A Tur; J Alfredo Martínez; M Angeles Zulet Journal: Nutrients Date: 2019-02-02 Impact factor: 5.717