Literature DB >> 27028435

Opportunities for the Cardiovascular Community in the Precision Medicine Initiative.

Svati H Shah1, Donna Arnett2, Steven R Houser2, Geoffrey S Ginsburg2, Calum MacRae2, Seema Mital2, Joseph Loscalzo2, Jennifer L Hall1.   

Abstract

The Precision Medicine Initiative recently announced by President Barack Obama seeks to move the field of precision medicine more rapidly into clinical care. Precision medicine revolves around the concept of integrating individual-level data including genomics, biomarkers, lifestyle and other environmental factors, wearable device physiological data, and information from electronic health records to ultimately provide better clinical care to individual patients. The Precision Medicine Initiative as currently structured will primarily fund efforts in cancer genomics with longer-term goals of advancing precision medicine to all areas of health, and will be supported through creation of a 1 million person cohort study across the United States. This focused effort on precision medicine provides scientists, clinicians, and patients within the cardiovascular community an opportunity to work together boldly to advance clinical care; the community needs to be aware and engaged in the process as it progresses. This article provides a framework for potential involvement of the cardiovascular community in the Precision Medicine Initiative, while highlighting significant challenges for its successful implementation.
© 2016 American Heart Association, Inc.

Entities:  

Keywords:  cardiovascular diseases; genetics; medicine, precision; risk factors

Mesh:

Year:  2016        PMID: 27028435     DOI: 10.1161/CIRCULATIONAHA.115.019475

Source DB:  PubMed          Journal:  Circulation        ISSN: 0009-7322            Impact factor:   29.690


  16 in total

Review 1.  Precision medicine in cardiology.

Authors:  Elliott M Antman; Joseph Loscalzo
Journal:  Nat Rev Cardiol       Date:  2016-06-30       Impact factor: 32.419

2.  Tailoring of medical treatment: hemostasis and thrombosis towards precision medicine.

Authors:  Giovanni Di Minno; Elena Tremoli
Journal:  Haematologica       Date:  2017-02-28       Impact factor: 9.941

Review 3.  Precision Medicine for Heart Failure with Preserved Ejection Fraction: An Overview.

Authors:  Sanjiv J Shah
Journal:  J Cardiovasc Transl Res       Date:  2017-06-05       Impact factor: 4.132

4.  Machine Learning Algorithm Predicts Cardiac Resynchronization Therapy Outcomes: Lessons From the COMPANION Trial.

Authors:  Matthew M Kalscheur; Ryan T Kipp; Matthew C Tattersall; Chaoqun Mei; Kevin A Buhr; David L DeMets; Michael E Field; Lee L Eckhardt; C David Page
Journal:  Circ Arrhythm Electrophysiol       Date:  2018-01

5.  Early somatic mosaicism is a rare cause of long-QT syndrome.

Authors:  James Rush Priest; Charles Gawad; Kristopher M Kahlig; Joseph K Yu; Thomas O'Hara; Patrick M Boyle; Sridharan Rajamani; Michael J Clark; Sarah T K Garcia; Scott Ceresnak; Jason Harris; Sean Boyle; Frederick E Dewey; Lindsey Malloy-Walton; Kyla Dunn; Megan Grove; Marco V Perez; Norma F Neff; Richard Chen; Katsuhide Maeda; Anne Dubin; Luiz Belardinelli; John West; Christian Antolik; Daniela Macaya; Thomas Quertermous; Natalia A Trayanova; Stephen R Quake; Euan A Ashley
Journal:  Proc Natl Acad Sci U S A       Date:  2016-09-28       Impact factor: 11.205

6.  Fractal Complexity of Daily Physical Activity Patterns Differs With Age Over the Life Span and Is Associated With Mortality in Older Adults.

Authors:  David A Raichlen; Yann C Klimentidis; Chiu-Hsieh Hsu; Gene E Alexander
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2019-08-16       Impact factor: 6.053

7.  SMRI Biomarkers Predict Electroconvulsive Treatment Outcomes: Accuracy with Independent Data Sets.

Authors:  Rongtao Jiang; Christopher C Abbott; Tianzi Jiang; Yuhui Du; Randall Espinoza; Katherine L Narr; Benjamin Wade; Qingbao Yu; Ming Song; Dongdong Lin; Jiayu Chen; Thomas Jones; Miklos Argyelan; Georgios Petrides; Jing Sui; Vince D Calhoun
Journal:  Neuropsychopharmacology       Date:  2017-07-31       Impact factor: 7.853

8.  Financing and Reimbursement Models for Personalised Medicine: A Systematic Review to Identify Current Models and Future Options.

Authors:  Rositsa Koleva-Kolarova; James Buchanan; Heleen Vellekoop; Simone Huygens; Matthijs Versteegh; Maureen Rutten-van Mölken; László Szilberhorn; Tamás Zelei; Balázs Nagy; Sarah Wordsworth; Apostolos Tsiachristas
Journal:  Appl Health Econ Health Policy       Date:  2022-04-04       Impact factor: 3.686

9.  The impact of creating mathematical formula to predict cardiovascular events in patients with heart failure.

Authors:  Mari Sakamoto; Hiroki Fukuda; Jiyoong Kim; Tomomi Ide; Shintaro Kinugawa; Arata Fukushima; Hiroyuki Tsutsui; Akira Ishii; Shin Ito; Hiroshi Asanuma; Masanori Asakura; Takashi Washio; Masafumi Kitakaze
Journal:  Sci Rep       Date:  2018-03-05       Impact factor: 4.379

Review 10.  Palliative treatment of coronary "atherosclerotic cancer" by drug-eluting or bare-metal stents: From oculo-stenotic reflex period to age of precision medicine.

Authors:  Elif Hande Ozcan Cetin; Ozcan Ozeke; Erdogan Ilkay; Dursun Aras; Serkan Topaloglu; Zehra Golbasi; Sinan Aydogdu; Can Ozer
Journal:  Indian Heart J       Date:  2017-07-14
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