Literature DB >> 27018778

Space Radiation and Human Exposures, A Primer.

Gregory A Nelson1.   

Abstract

The space radiation environment is a complex field comprised primarily of charged particles spanning energies over many orders of magnitude. The principal sources of these particles are galactic cosmic rays, the Sun and the trapped radiation belts around the earth. Superimposed on a steady influx of cosmic rays and a steady outward flux of low-energy solar wind are short-term ejections of higher energy particles from the Sun and an 11-year variation of solar luminosity that modulates cosmic ray intensity. Human health risks are estimated from models of the radiation environment for various mission scenarios, the shielding of associated vehicles and the human body itself. Transport models are used to propagate the ambient radiation fields through realistic shielding levels and materials to yield radiation field models inside spacecraft. Then, informed by radiobiological experiments and epidemiology studies, estimates are made for various outcome measures associated with impairments of biological processes, losses of function or mortality. Cancer-associated risks have been formulated in a probabilistic model while management of non-cancer risks are based on permissible exposure limits. This article focuses on the various components of the space radiation environment and the human exposures that it creates.

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Year:  2016        PMID: 27018778     DOI: 10.1667/RR14311.1

Source DB:  PubMed          Journal:  Radiat Res        ISSN: 0033-7587            Impact factor:   2.841


  41 in total

1.  Changes in one-carbon metabolism and DNA methylation in the hearts of mice exposed to space environment-relevant doses of oxygen ions (16O).

Authors:  Isabelle R Miousse; Charles M Skinner; Vijayalakshmi Sridharan; John W Seawright; Preeti Singh; Reid D Landes; Amrita K Cheema; Martin Hauer-Jensen; Marjan Boerma; Igor Koturbash
Journal:  Life Sci Space Res (Amst)       Date:  2019-05-31

2.  Effects of 1H + 16O Charged Particle Irradiation on Short-Term Memory and Hippocampal Physiology in a Murine Model.

Authors:  Frederico Kiffer; Hannah Carr; Thomas Groves; Julie E Anderson; Tyler Alexander; Jing Wang; John W Seawright; Vijayalakshmi Sridharan; Gwendolyn Carter; Marjan Boerma; Antiño R Allen
Journal:  Radiat Res       Date:  2017-11-14       Impact factor: 2.841

3.  Alterations in synaptic density and myelination in response to exposure to high-energy charged particles.

Authors:  Dara L Dickstein; Ronan Talty; Erin Bresnahan; Merina Varghese; Bayley Perry; William G M Janssen; Allison Sowa; Erich Giedzinski; Lauren Apodaca; Janet Baulch; Munjal Acharya; Vipan Parihar; Charles L Limoli
Journal:  J Comp Neurol       Date:  2018-11-08       Impact factor: 3.215

4.  Reflections on Basic Science Studies Involving Low Doses of Ionizing Radiation.

Authors:  Tatjana Paunesku; Gayle Woloschak
Journal:  Health Phys       Date:  2018-11       Impact factor: 1.316

Review 5.  Behavioral effects of space radiation: A comprehensive review of animal studies.

Authors:  Frederico Kiffer; Marjan Boerma; Antiño Allen
Journal:  Life Sci Space Res (Amst)       Date:  2019-02-19

Review 6.  Role of High-Linear Energy Transfer Radiobiology in Space Radiation Exposure Risks.

Authors:  Akihisa Takahashi; Hiroko Ikeda; Yukari Yoshida
Journal:  Int J Part Ther       Date:  2018-09-21

7.  Influence of Cranial Irradiation with High-Energy Protons on the Visuomotor Behavior in Monkeys.

Authors:  A V Latanov; L V Tereschenko; M A Ostrovsky
Journal:  Dokl Biol Sci       Date:  2019-09-30

8.  Late effects of 1H irradiation on hippocampal physiology.

Authors:  Frederico Kiffer; Alexis K Howe; Hannah Carr; Jing Wang; Tyler Alexander; Julie E Anderson; Thomas Groves; John W Seawright; Vijayalakshmi Sridharan; Gwendolyn Carter; Marjan Boerma; Antiño R Allen
Journal:  Life Sci Space Res (Amst)       Date:  2018-03-15

Review 9.  Planetary extravehicular activity (EVA) risk mitigation strategies for long-duration space missions.

Authors:  Blaze Belobrajdic; Kate Melone; Ana Diaz-Artiles
Journal:  NPJ Microgravity       Date:  2021-05-12       Impact factor: 4.415

10.  Female mice are protected from space radiation-induced maladaptive responses.

Authors:  Karen Krukowski; Katherine Grue; Elma S Frias; John Pietrykowski; Tamako Jones; Gregory Nelson; Susanna Rosi
Journal:  Brain Behav Immun       Date:  2018-08-11       Impact factor: 7.217

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