Literature DB >> 31773027

Role of High-Linear Energy Transfer Radiobiology in Space Radiation Exposure Risks.

Akihisa Takahashi1, Hiroko Ikeda2, Yukari Yoshida1.   

Abstract

Many manned missions to the Moon and Mars are scheduled in the near future. However, space radiation presents a major hazard to humans, and astronauts are constantly exposed to radiation, including high linear energy transfer (LET) radiation, which differs from radiation on Earth. Thus, there is thus an urgent need to clarify the biological effects of space radiation and reduce the associated risks. In this review, we consider the role of high-LET radiobiology in relation to space-radiation exposure. ©Copyright 2018 International Journal of Particle Therapy.

Entities:  

Keywords:  linear energy transfer; radiobiology; risk assessment; space radiation

Year:  2018        PMID: 31773027      PMCID: PMC6871591          DOI: 10.14338/IJPT-18-00013.1

Source DB:  PubMed          Journal:  Int J Part Ther        ISSN: 2331-5180


  58 in total

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Journal:  Br J Radiol       Date:  2014-03       Impact factor: 3.039

6.  Detection of DNA damage by space radiation in human fibroblasts flown on the International Space Station.

Authors:  Tao Lu; Ye Zhang; Michael Wong; Alan Feiveson; Ramona Gaza; Nicholas Stoffle; Huichen Wang; Bobby Wilson; Larry Rohde; Louis Stodieck; Fathi Karouia; Honglu Wu
Journal:  Life Sci Space Res (Amst)       Date:  2016-12-24

7.  Overview of the NASA space radiation laboratory.

Authors:  Chiara La Tessa; Michael Sivertz; I-Hung Chiang; Derek Lowenstein; Adam Rusek
Journal:  Life Sci Space Res (Amst)       Date:  2016-11-11

Review 8.  Initial events in the cellular effects of ionizing radiations: clustered damage in DNA.

Authors:  D T Goodhead
Journal:  Int J Radiat Biol       Date:  1994-01       Impact factor: 2.694

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10.  Galactic cosmic radiation leads to cognitive impairment and increased aβ plaque accumulation in a mouse model of Alzheimer's disease.

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Journal:  PLoS One       Date:  2012-12-31       Impact factor: 3.240

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  7 in total

Review 1.  Ionizing Radiation as a Source of Oxidative Stress-The Protective Role of Melatonin and Vitamin D.

Authors:  Jarosław Nuszkiewicz; Alina Woźniak; Karolina Szewczyk-Golec
Journal:  Int J Mol Sci       Date:  2020-08-13       Impact factor: 5.923

Review 2.  Influence of Microgravity on Apoptosis in Cells, Tissues, and Other Systems In Vivo and In Vitro.

Authors:  Binod Prasad; Daniela Grimm; Sebastian M Strauch; Gilmar Sidnei Erzinger; Thomas J Corydon; Michael Lebert; Nils E Magnusson; Manfred Infanger; Peter Richter; Marcus Krüger
Journal:  Int J Mol Sci       Date:  2020-12-09       Impact factor: 5.923

Review 3.  Biological Protection in Deep Space Missions.

Authors:  Lembit Sihver; Seyed Mohammad Javad Mortazavi
Journal:  J Biomed Phys Eng       Date:  2021-12-01

4.  Fidelity of a Bacterial DNA Polymerase in Microgravity, a Model for Human Health in Space.

Authors:  Aaron H Rosenstein; Virginia K Walker
Journal:  Front Cell Dev Biol       Date:  2021-11-29

Review 5.  Space Radiation Biology for "Living in Space".

Authors:  Satoshi Furukawa; Aiko Nagamatsu; Mitsuru Nenoi; Akira Fujimori; Shizuko Kakinuma; Takanori Katsube; Bing Wang; Chizuru Tsuruoka; Toshiyuki Shirai; Asako J Nakamura; Asako Sakaue-Sawano; Atsushi Miyawaki; Hiroshi Harada; Minoru Kobayashi; Junya Kobayashi; Takekazu Kunieda; Tomoo Funayama; Michiyo Suzuki; Tatsuo Miyamoto; Jun Hidema; Yukari Yoshida; Akihisa Takahashi
Journal:  Biomed Res Int       Date:  2020-04-08       Impact factor: 3.411

6.  Combined Environment Simulator for Low-Dose-Rate Radiation and Partial Gravity of Moon and Mars.

Authors:  Akihisa Takahashi; Sakuya Yamanouchi; Kazuomi Takeuchi; Shogo Takahashi; Mutsumi Tashiro; Jun Hidema; Atsushi Higashitani; Takuya Adachi; Shenke Zhang; Fady Nagy Lotfy Guirguis; Yukari Yoshida; Aiko Nagamatsu; Megumi Hada; Kunihito Takeuchi; Tohru Takahashi; Yuji Sekitomi
Journal:  Life (Basel)       Date:  2020-11-06

Review 7.  MicroRNAs Responding to Space Radiation.

Authors:  Yujie Yan; Kunlan Zhang; Guangming Zhou; Wentao Hu
Journal:  Int J Mol Sci       Date:  2020-09-09       Impact factor: 5.923

  7 in total

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