Chuang Chen1, Si Sun2, Jing-Ping Yuan3, Yao-Huai Wang1, Tian-Ze Cao1, Hong-Mei Zheng4, Xue-Qing Jiang5, Yi-Ping Gong6, Yi Tu1, Feng Yao1, Ming-Bai Hu7, Juan-Juan Li1, Sheng-Rong Sun1, Wen Wei8. 1. Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, PR China. 2. Department of Clinical Laboratory Medicine Center, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, PR China. 3. Department of Pathology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, PR China. 4. Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, PR China; Department of Breast Surgery, Hubei Cancer Hospital, Wuhan, Hubei 430079, PR China. 5. Department of Breast and Thyroid Surgery, The Central Hospital of Wuhan, Wuhan, Hubei 430014, PR China. 6. Department of Breast Surgery, Hubei Cancer Hospital, Wuhan, Hubei 430079, PR China. 7. Department of Oncology, Zhongnan Hospital of Wuhan University, Wuhan 430071, PR China. 8. Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, PR China. Electronic address: 99161305@qq.com.
Abstract
INTRODUCTION: This work was to analyze characteristics of breast cancer (BC) in Central China, summarize main characteristics in China and compare with USA. METHODS: BC main characteristics from four hospitals in Central China from 2002 to 2012 were collected and analyzed. All the single and large-scale clinical reports covering at least ten years were selected and summarized to calculate the BC characteristics of China. BC Characteristics in USA were selected based on the database from Surveillance, Epidemiology, and End Results (SEER) Program. RESULTS: Age distribution in Central China was normal with one age peak at 45-49 years, displaying differences from USA and Chinese American with two age peaks. BC characteristics in Central China displayed distinct features from USA and Chinese American, including significant younger onset age, lower proportion of patients with stage I, lymph node negative, small tumor size and ER positive. A total ten long-term and large-scale clinical reports were selected for BC characteristics of Mainland China analysis. A total of 53,571 BC patients were enrolled from 1995 to 2012. The main characteristics of BC in Mainland China were similar as that in Central China, but were significant different from developed regions of China (Hong Kong and Taiwan), USA and Chinese American. CONCLUSIONS: BC characteristics in Central China displayed representative patterns of Mainland China, while showed distinct patterns from Chinese patients in other developed areas and USA.
INTRODUCTION: This work was to analyze characteristics of breast cancer (BC) in Central China, summarize main characteristics in China and compare with USA. METHODS: BC main characteristics from four hospitals in Central China from 2002 to 2012 were collected and analyzed. All the single and large-scale clinical reports covering at least ten years were selected and summarized to calculate the BC characteristics of China. BC Characteristics in USA were selected based on the database from Surveillance, Epidemiology, and End Results (SEER) Program. RESULTS: Age distribution in Central China was normal with one age peak at 45-49 years, displaying differences from USA and Chinese American with two age peaks. BC characteristics in Central China displayed distinct features from USA and Chinese American, including significant younger onset age, lower proportion of patients with stage I, lymph node negative, small tumor size and ER positive. A total ten long-term and large-scale clinical reports were selected for BC characteristics of Mainland China analysis. A total of 53,571 BC patients were enrolled from 1995 to 2012. The main characteristics of BC in Mainland China were similar as that in Central China, but were significant different from developed regions of China (Hong Kong and Taiwan), USA and Chinese American. CONCLUSIONS: BC characteristics in Central China displayed representative patterns of Mainland China, while showed distinct patterns from Chinese patients in other developed areas and USA.
Authors: Alessandro Fancellu; Xue Yun Zhao; Pietrina Cottu; Valeria Sanna; Yuan Ping Li; Qin Zhu; Cinzia Tanda; Ying Yi Zhang; Yan Mei Lai; Giorgio Carlo Ginesu; Shu Qin Dai; Alberto Porcu Journal: Breast Care (Basel) Date: 2020-01-21 Impact factor: 2.860