Literature DB >> 27003393

Novel domino procedures for the synthesis of chromene derivatives and their isomerization.

Afsaneh Zonouzi1,2, Zakieh Izakian3,4, Seik Weng Ng5,6.   

Abstract

Novel tricyclic keto diesters have been synthesized by a one-pot three-component procedure via DABCO-catalyzed domino Knoevenagel-Michael addition reactions. Also, an efficient four-component reaction for the synthesis of another new group of tricyclic keto diesters has been developed via domino Knoevenagel-intramolecular oxo-Diels-Alder reactions. A selective thermal isomerization of the synthesized chromenes to fumarates is also described. X-ray analyses confirm unambiguously the structures of the products.

Entities:  

Keywords:  Chromene; DABCO; Domino reaction; Iminolactone; Isomerization; MCRs; Michael addition; Oxo-Diels–Alder

Mesh：

Substances：

Year:  2016        PMID： 27003393     DOI： 10.1007/s11030-016-9664-0

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  11 in total

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