Literature DB >> 27000288

Cancer-disease associations: A visualization and animation through medical big data.

Usman Iqbal1, Chun-Kung Hsu1, Phung Anh Alex Nguyen1, Daniel Livius Clinciu1, Richard Lu1, Shabbir Syed-Abdul1, Hsuan-Chia Yang2, Yao-Chin Wang3, Chu-Ya Huang3, Chih-Wei Huang1, Yo-Cheng Chang3, Min-Huei Hsu4, Wen-Shan Jian5, Yu-Chuan Jack Li6.   

Abstract

OBJECTIVE: Cancer is the primary disease responsible for death and disability worldwide. Currently, prevention and early detection represents the best hope for cure. Knowing the expected diseases that occur with a particular cancer in advance could lead to physicians being able to better tailor their treatment for cancer. The aim of this study was to build an animated visualization tool called as Cancer Associations Map Animation (CAMA), to chart the association of cancers with other disease over time.
METHODS: The study population was collected from the Taiwan National Health Insurance Database during the period January 2000 to December 2002, 782 million outpatient visits were used to compute the associations of nine major cancers with other diseases. A motion chart was used to quantify and visualize the associations between diseases and cancers.
RESULTS: The CAMA motion chart that was built successfully facilitated the observation of cancer-disease associations across ages and genders. The CAMA system can be accessed online at http://203.71.86.98/web/runq16.html.
CONCLUSION: The CAMA animation system is an animated medical data visualization tool which provides a dynamic, time-lapse, animated view of cancer-disease associations across different age groups and gender. Derived from a large, nationwide healthcare dataset, this exploratory data analysis tool can detect cancer comorbidities earlier than is possible by manual inspection. Taking into account the trajectory of cancer-specific comorbidity development may facilitate clinicians and healthcare researchers to more efficiently explore early stage hypotheses, develop new cancer treatment approaches, and identify potential effect modifiers or new risk factors associated with specific cancers.
Copyright © 2016. Published by Elsevier Ireland Ltd.

Entities:  

Keywords:  Big data visualization; Cancer comorbidities visualization; Cancer disease visualization; Disease visualization; Visual analytics

Mesh:

Year:  2016        PMID: 27000288     DOI: 10.1016/j.cmpb.2016.01.009

Source DB:  PubMed          Journal:  Comput Methods Programs Biomed        ISSN: 0169-2607            Impact factor:   5.428


  5 in total

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Review 2.  What Can We Learn About Drug Safety and Other Effects in the Era of Electronic Health Records and Big Data That We Would Not Be Able to Learn From Classic Epidemiology?

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Journal:  J Surg Res       Date:  2019-10-22       Impact factor: 2.192

Review 3.  A Systematic Review on Healthcare Analytics: Application and Theoretical Perspective of Data Mining.

Authors:  Md Saiful Islam; Md Mahmudul Hasan; Xiaoyi Wang; Hayley D Germack; Md Noor-E-Alam
Journal:  Healthcare (Basel)       Date:  2018-05-23

4.  Detection of Benign and Malignant Tumors in Skin Empowered with Transfer Learning.

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Journal:  Comput Intell Neurosci       Date:  2022-03-24

5.  Diabetes classification model based on boosting algorithms.

Authors:  Peihua Chen; Chuandi Pan
Journal:  BMC Bioinformatics       Date:  2018-03-27       Impact factor: 3.169

  5 in total

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