| Literature DB >> 26998252 |
Aline A Ishikawa1, Jesus V Salazar2, Magaly Salinas3, Cristiane M Gaitani4, Timothy Nurkiewicz5, George R Negrete3, Carlos D Garcia6.
Abstract
Rifampicin (RIF) is a benchmark drug for treatment of tuberculosis, but poor bioavailability, prolonged treatment, and pill burden have been linked to therapeutic failure and the development of multidrug resistant strains. To overcome these limitations, this study investigated a method of rifampicin nanoencapsulation and aerosol delivery using a commercial, hand-held nebulizer modified with a nitrogen stream.Entities:
Year: 2016 PMID: 26998252 PMCID: PMC4792303 DOI: 10.1039/C5RA25044G
Source DB: PubMed Journal: RSC Adv ISSN: 2046-2069 Impact factor: 3.361