Muhammet Kazim Erol1, Ayse Balkarli2, Devrim Toslak3, Berna Dogan3, Dogan Durmaz3, Elçin Süren3, Salih Altun4, Mehmet Bulut3, Veli Cobankara5. 1. Department of Ophtholmology, Antalya Education and Research Hospital, Kazim Karabekir Avenue, 07720, Muratpaşa, Antalya, Turkey. muhammetkazimerol@gmail.com. 2. Department of Internal Medicine, Division of Rheumatology, Antalya Education and Research Hospital, Antalya, Turkey. 3. Department of Ophtholmology, Antalya Education and Research Hospital, Kazim Karabekir Avenue, 07720, Muratpaşa, Antalya, Turkey. 4. Department of Ophtholmology, Gulhane Military Medical Academy, Ankara, Turkey. 5. Department of Internal Medicine, Division of Rheumatology, Pamukkale University Hospital, Denizli, Turkey.
Abstract
BACKGROUND: Nailfold videocapillaroscopy (NVC) is a diagnostic tool to evaluate micro-vasculature. The presence of choroidal vasculopathy is apparent in central serous chorioretinopathy (CSCR). OBJECTIVES: This study was aimed at assessing capillaroscopic nailfold findings in patients with CSCR. To the best of our knowledge, there is no study assessing NVC findings in CSCR in the literature. METHOD: Sixty-one patients with CSCR who met the inclusion criteria, and 82 age- and sex-matched healthy controls were included to the study. A videocapillaroscopy device with 200× magnification was used for capillaroscopic assessment. RESULTS: The mean age was 48.79 ± 11.15 years in the patient group (13 female, 48 male) and 49.38 ± 9.02 years in the control group (17 female, 65 male). The age and gender were comparable in the patient and control groups (p = 0.727 and p = 0.933, respectively). The capillary count was found to be decreased in the patient group compared to control group. No significant correlation was found between capillary count and choroidal thickness (p = 0.551; r = -0.081). In the patient group, the frequencies of major capillaroscopic findings including capillary ectasia, aneurysm, micro-hemorrhage, avascular area, tortuosity, neo-formation, bizarre capillary, bushy capillary, meander capillary and extravasation were found to be increased in the patient group. However, no significant correlation was detected between capillaroscopic findings and disease type and presence of attacks. CONCLUSIONS: This is first study in which nailfold capillary assessment was performed in patients with CSCR, and we detected major capillaroscopic changes. These findings suggest that CSCR can be a systemic microvasculopathy. Further studies are needed to clarify the diagnostic and prognostic value of capillaroscopy in CSCR.
BACKGROUND: Nailfold videocapillaroscopy (NVC) is a diagnostic tool to evaluate micro-vasculature. The presence of choroidal vasculopathy is apparent in central serous chorioretinopathy (CSCR). OBJECTIVES: This study was aimed at assessing capillaroscopic nailfold findings in patients with CSCR. To the best of our knowledge, there is no study assessing NVC findings in CSCR in the literature. METHOD: Sixty-one patients with CSCR who met the inclusion criteria, and 82 age- and sex-matched healthy controls were included to the study. A videocapillaroscopy device with 200× magnification was used for capillaroscopic assessment. RESULTS: The mean age was 48.79 ± 11.15 years in the patient group (13 female, 48 male) and 49.38 ± 9.02 years in the control group (17 female, 65 male). The age and gender were comparable in the patient and control groups (p = 0.727 and p = 0.933, respectively). The capillary count was found to be decreased in the patient group compared to control group. No significant correlation was found between capillary count and choroidal thickness (p = 0.551; r = -0.081). In the patient group, the frequencies of major capillaroscopic findings including capillary ectasia, aneurysm, micro-hemorrhage, avascular area, tortuosity, neo-formation, bizarre capillary, bushy capillary, meander capillary and extravasation were found to be increased in the patient group. However, no significant correlation was detected between capillaroscopic findings and disease type and presence of attacks. CONCLUSIONS: This is first study in which nailfold capillary assessment was performed in patients with CSCR, and we detected major capillaroscopic changes. These findings suggest that CSCR can be a systemic microvasculopathy. Further studies are needed to clarify the diagnostic and prognostic value of capillaroscopy in CSCR.
Entities:
Keywords:
Central serous chorioretinopathy; Choroidal vasculopathy; Nailfold videocapillaroscopy
Authors: Mehmet Fatih Küçük; Ayşe Ayan; Devrim Toslak; Elçin Süren; Lütfiye Yaprak; Ersan Çetinkaya; Muhammet Kazım Erol; Deniz Turgut Çoban Journal: Ir J Med Sci Date: 2019-10-24 Impact factor: 1.568