Literature DB >> 26988555

Surgical site infections following operative management of cervical spondylotic myelopathy: prevalence, predictors of occurence, and influence on peri-operative outcomes.

C M Jalai1, N Worley1, G W Poorman1, D L Cruz1, S Vira1, P G Passias2,3.   

Abstract

PURPOSE: Studies have examined infection rates following spine surgery and their relationship to post-operative complications and increased length of stay. Few studies, however, have investigated predictors of infection, specifically in the setting of operative intervention for cervical spondylotic myelopathy (CSM). This study aims to identify the incidence and factors predictive of infection amongst this cohort.
METHODS: This study performed a retrospective review of the prospectively collected American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database. Patients included those treated surgically for CSM (ICD-9 code 721.1) from 2010 to 2012. Patient demographics and surgical data were collected with outcome variables including the occurrence of one of the following surgical site infections (SSIs) within 30 days of index operation: superficial SSI, deep incisional SSI, and organ/space SSI.
RESULTS: 3057 patients were included in this analysis. Overall infection rate was 1.15 % (35/3057), of which 54.3 % (19/35) were superficial SSIs, 28.6 % (10/35) were deep incisional SSI, and 20 % (7/35) were peri-spinal SSI. Logistic regression revealed factors associated with SSI included: higher BMI [OR 1.162 (CI 1.269-1.064), p = 0.001] and operative time ≥208 min [OR 4.769 (CI 20.220-1.125), p = 0.034].
CONCLUSIONS: The overall SSI rate for the examined CSM cohort was 1.15 %. This study identified increased BMI and operative time ≥208 min as predictors of infection in surgical CSM patients. This information should be carefully considered in delivering patient education and future efforts to optimize risk in CSM patients indicated for surgical intervention.

Entities:  

Keywords:  Cervical spondylotic myelopathy; National Surgical Quality Improvement Program; Peri-operative outcomes; Surgical site infection

Mesh:

Year:  2016        PMID: 26988555     DOI: 10.1007/s00586-016-4501-9

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  28 in total

Review 1.  What is new in the diagnosis and prevention of spine surgical site infections.

Authors:  Kris E Radcliff; Alexander D Neusner; Paul W Millhouse; James D Harrop; Christopher K Kepler; Mohammad R Rasouli; Todd J Albert; Alexander R Vaccaro
Journal:  Spine J       Date:  2014-09-28       Impact factor: 4.166

2.  Intrawound vancomycin powder reduces surgical site infections in posterior cervical fusion.

Authors:  Cyrus Caroom; Jessica M Tullar; E Garrison Benton; Jason R Jones; Christopher D Chaput
Journal:  Spine (Phila Pa 1976)       Date:  2013-06-15       Impact factor: 3.468

Review 3.  Evidence-based management of deep wound infection after spinal instrumentation.

Authors:  Rishi R Lall; Albert P Wong; Rohan R Lall; Cort D Lawton; Zachary A Smith; Nader S Dahdaleh
Journal:  J Clin Neurosci       Date:  2014-10-11       Impact factor: 1.961

4.  Postoperative spinal wound infection: a review of 2,391 consecutive index procedures.

Authors:  M A Weinstein; J P McCabe; F P Cammisa
Journal:  J Spinal Disord       Date:  2000-10

5.  Risk Factors for Postoperative Infections After Single-Level Lumbar Fusion Surgery.

Authors:  Seokchun Lim; Adam I Edelstein; Alpesh A Patel; Bobby D Kim; John Y S Kim
Journal:  Spine (Phila Pa 1976)       Date:  2018-02-01       Impact factor: 3.468

Review 6.  Infections after spinal correction and fusion for spinal deformities in childhood and adolescence.

Authors:  Manon Bachy; Benjamin Bouyer; Raphaël Vialle
Journal:  Int Orthop       Date:  2011-12-11       Impact factor: 3.075

7.  Perioperative and delayed complications associated with the surgical treatment of cervical spondylotic myelopathy based on 302 patients from the AOSpine North America Cervical Spondylotic Myelopathy Study.

Authors:  Michael G Fehlings; Justin S Smith; Branko Kopjar; Paul M Arnold; S Tim Yoon; Alexander R Vaccaro; Darrel S Brodke; Michael E Janssen; Jens R Chapman; Rick C Sasso; Eric J Woodard; Robert J Banco; Eric M Massicotte; Mark B Dekutoski; Ziya L Gokaslan; Christopher M Bono; Christopher I Shaffrey
Journal:  J Neurosurg Spine       Date:  2012-02-10

8.  Surgical management of cervical spondylotic myelopathy with laminectomy and instrumented fusion.

Authors:  Beril Gok; Gregory S McLoughlin; Daniel M Sciubba; Mathew J McGirt; Kaisorn L Chaichana; Jean-Paul Wolinsky; Ali Bydon; Ziya L Gokaslan; Timothy F Witham
Journal:  Neurol Res       Date:  2009-02-11       Impact factor: 2.448

9.  Is surgery for cervical spondylotic myelopathy cost-effective? A cost-utility analysis based on data from the AOSpine North America prospective CSM study.

Authors:  Michael G Fehlings; Neilank K Jha; Stephanie M Hewson; Eric M Massicotte; Branko Kopjar; Sukhvinder Kalsi-Ryan
Journal:  J Neurosurg Spine       Date:  2012-09

10.  A prospective randomized controlled trial of anterior compared with posterior stabilization for unilateral facet injuries of the cervical spine.

Authors:  Brian K Kwon; Charles G Fisher; Michael C Boyd; John Cobb; Hilary Jebson; Vanessa Noonan; Peter Wing; Marcel F Dvorak
Journal:  J Neurosurg Spine       Date:  2007-07
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  6 in total

1.  Risk factors for wound complications following spine surgery.

Authors:  Keaton F Piper; Samuel B Tomlinson; Gabrielle Santangelo; Joseph Van Galen; Ian DeAndrea-Lazarus; James Towner; Kristopher T Kimmell; Howard Silberstein; George Edward Vates
Journal:  Surg Neurol Int       Date:  2017-11-01

2.  Surgical Site Infection in Spine Surgery: Who Is at Risk?

Authors:  Reina Yao; Hanbing Zhou; Theodore J Choma; Brian K Kwon; John Street
Journal:  Global Spine J       Date:  2018-12-13

3.  Tissue discrimination by bioelectrical impedance during PLL resection in anterior decompression surgery for treatment of cervical spondylotic myelopathy.

Authors:  Fuqiang Shao; He Bai; Muyao Tang; Yuan Xue; Yu Dai; Jianxun Zhang
Journal:  J Orthop Surg Res       Date:  2019-11-06       Impact factor: 2.359

Review 4.  The Role of Nutrition in Degenerative Cervical Myelopathy: A Systematic Review.

Authors:  Celine I Partha Sarathi; Oliver D Mowforth; Amil Sinha; Faheem Bhatti; Aniqah Bhatti; Melika Akhbari; Shahzaib Ahmed; Benjamin M Davies
Journal:  Nutr Metab Insights       Date:  2021-10-30

5.  Risk Factors for Postoperative Deep Infection after Instrumented Spinal Fusion Surgeries for Degenerative Spinal Disease: A Nationwide Cohort Study of 194,036 Patients.

Authors:  Jihye Kim; Tae-Hwan Kim
Journal:  J Clin Med       Date:  2022-01-31       Impact factor: 4.241

Review 6.  Preclinical models of vertebral osteomyelitis and associated infections: Current models and recommendations for study design.

Authors:  Kieran Joyce; Daisuke Sakai; Abhay Pandit
Journal:  JOR Spine       Date:  2021-03-02
  6 in total

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