Literature DB >> 26974193

Mitochondria-specific conjugated polymer nanoparticles.

Megan Twomey1, Eladio Mendez, Rajesh Kumar Manian, Sunwoo Lee, Joong Ho Moon.   

Abstract

Biodegradable conjugated polymer nanoparticles (CPNs) were prepared for high mitochondrial targeting in live cancer cells. The degradable CPNs are nontoxic and specifically localized to the mitochondria of live tumor cells through macropinocytosis followed by intracellular degradation and trafficking.

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Year:  2016        PMID： 26974193      PMCID： PMC4821631          DOI： 10.1039/c6cc00810k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  16 in total

1.  Highly sensitive biological and chemical sensors based on reversible fluorescence quenching in a conjugated polymer.

Authors:  L Chen; D W McBranch; H L Wang; R Helgeson; F Wudl; D G Whitten
Journal:  Proc Natl Acad Sci U S A       Date:  1999-10-26       Impact factor: 11.205

2.  Live-cell-permeable poly(p-phenylene ethynylene).

Authors:  Joong Ho Moon; William McDaniel; Paul Maclean; Lawrence F Hancock
Journal:  Angew Chem Int Ed Engl       Date:  2007       Impact factor: 15.336

3.  Colorimetric and fluorometric detection of nucleic acids using cationic polythiophene derivatives.

Authors:  Hoang-Anh Ho; Maurice Boissinot; Michel G Bergeron; Geneviève Corbeil; Kim Doré; Denis Boudreau; Mario Leclerc
Journal:  Angew Chem Int Ed Engl       Date:  2002-05-03       Impact factor: 15.336

Review 4.  Conjugated polymer nanoparticles: preparation, properties, functionalization and biological applications.

Authors:  Liheng Feng; Chunlei Zhu; Huanxiang Yuan; Libing Liu; Fengting Lv; Shu Wang
Journal:  Chem Soc Rev       Date:  2013-08-21       Impact factor: 54.564

5.  The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls.

Authors:  Dries Vercauteren; Roosmarijn E Vandenbroucke; Arwyn T Jones; Joanna Rejman; Joseph Demeester; Stefaan C De Smedt; Niek N Sanders; Kevin Braeckmans
Journal:  Mol Ther       Date:  2009-12-15       Impact factor: 11.454

6.  A highly emissive conjugated polyelectrolyte vector for gene delivery and transfection.

Authors:  Xuli Feng; Fengting Lv; Libing Liu; Qiong Yang; Shu Wang; Guillermo C Bazan
Journal:  Adv Mater       Date:  2012-08-07       Impact factor: 30.849

7.  Multicolor conjugated polymer dots for biological fluorescence imaging.

Authors:  Changfeng Wu; Barbara Bull; Craig Szymanski; Kenneth Christensen; Jason McNeill
Journal:  ACS Nano       Date:  2008-11-25       Impact factor: 15.881

8.  Synthesis of phenyleneethynylene-doped poly(pphenylenebutadiynylene) s for live cell imaging.

Authors:  Tereza Vokatá; Joong Ho Moon
Journal:  Macromolecules       Date:  2013-01-25       Impact factor: 5.985

Review 9.  Targeting mitochondria.

Authors:  Adam T Hoye; Jennifer E Davoren; Peter Wipf; Mitchell P Fink; Valerian E Kagan
Journal:  Acc Chem Res       Date:  2008-01       Impact factor: 22.384

10.  Side chain and backbone structure-dependent subcellular localization and toxicity of conjugated polymer nanoparticles.

Authors:  Eladio Mendez; Joong Ho Moon
Journal:  Chem Commun (Camb)       Date:  2013-07-11       Impact factor: 6.222
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  1 in total

Review 1.  Recent Advances in the Development of Highly Luminescent Semiconducting Polymer Dots and Nanoparticles for Biological Imaging and Medicine.

Authors:  Jiangbo Yu; Yu Rong; Chun-Ting Kuo; Xing-Hua Zhou; Daniel T Chiu
Journal:  Anal Chem       Date:  2016-12-08       Impact factor: 6.986
  1 in total

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