Ming-Li Li1, Yu-Yuan Xu2, Bo Hou3, Zhao-Yong Sun4, Hai-Long Zhou5, Zheng-Yu Jin6, Feng Feng7, Wei-Hai Xu8. 1. Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China. Electronic address: limingli@pumch.cn. 2. Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China. Electronic address: atlantis-1@163.com. 3. Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China. Electronic address: hb8680@qq.com. 4. Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China. Electronic address: szy_2004@163.com. 5. Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China. Electronic address: Zhouhailong1028@126.com. 6. Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China. Electronic address: jin_zhengyu@163.com. 7. Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China. Electronic address: cjr.fengfeng@vip.163.com. 8. Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China. Electronic address: xuwh@pumch.cn.
Abstract
PURPOSE: To evaluate the feasibility of high-resolution 3D CUBE T1WI for intracranial vessel wall imaging. METHODS: High-resolution 3D CUBE T1 weighted intracranial vessel wall images (0.4 mm × 0.4 mm × 0.4 mm) of 50 patients were retrospectively evaluated. A 5-point scale (1 poor, 5 excellent) was used to score the imaging quality for displaying the vessel wall of every intracranial artery segments. The inter-observer and intra-observer reproducibility of identifying plaques, intraplaque hemorrhage/luminal thrombosis, and wall enhancement were calculated. RESULTS: Totally 893 artery segments were evaluated. 3D CUBE T1WI displayed the arteries wall and lumen clearly, with the highest score (4.920 ± 0.837) for the C6-7 segments and the lowest (3.370 ± 1.107) for the C3 segments of the internal carotid artery (ICA). Both intra-observer and inter-observer reproducibility were high for identification of normal walls (κ=0.928, 95% confidence interval [CI] 0.891-0.954; κ=0.911, CI 0.868-0.940), plaque (κ=0.924, CI 0.884-0.954; κ=0.907, CI 0.866-0.943), luminal thrombosis (κ=1.000, CI 1.000-1.000; κ=1.000, CI 1.000-1.000), and wall enhancement (κ=1.000, CI 1.000-1.000; κ=0.914, CI 0.863-0.961). CONCLUSIONS: High-resolution 3D CUBE T1WI displayed intracranial wall and lumen clearly, and detected intracranial artery abnormalities with high reproducibility.
PURPOSE: To evaluate the feasibility of high-resolution 3D CUBE T1WI for intracranial vessel wall imaging. METHODS: High-resolution 3D CUBE T1 weighted intracranial vessel wall images (0.4 mm × 0.4 mm × 0.4 mm) of 50 patients were retrospectively evaluated. A 5-point scale (1 poor, 5 excellent) was used to score the imaging quality for displaying the vessel wall of every intracranial artery segments. The inter-observer and intra-observer reproducibility of identifying plaques, intraplaque hemorrhage/luminal thrombosis, and wall enhancement were calculated. RESULTS: Totally 893 artery segments were evaluated. 3D CUBE T1WI displayed the arteries wall and lumen clearly, with the highest score (4.920 ± 0.837) for the C6-7 segments and the lowest (3.370 ± 1.107) for the C3 segments of the internal carotid artery (ICA). Both intra-observer and inter-observer reproducibility were high for identification of normal walls (κ=0.928, 95% confidence interval [CI] 0.891-0.954; κ=0.911, CI 0.868-0.940), plaque (κ=0.924, CI 0.884-0.954; κ=0.907, CI 0.866-0.943), luminal thrombosis (κ=1.000, CI 1.000-1.000; κ=1.000, CI 1.000-1.000), and wall enhancement (κ=1.000, CI 1.000-1.000; κ=0.914, CI 0.863-0.961). CONCLUSIONS: High-resolution 3D CUBE T1WI displayed intracranial wall and lumen clearly, and detected intracranial artery abnormalities with high reproducibility.
Authors: Jae W Song; Brianna F Moon; Morgan P Burke; Srikant Kamesh Iyer; Mark A Elliott; Haochang Shou; Steven R Messé; Scott E Kasner; Laurie A Loevner; Mitchell D Schnall; John E Kirsch; Walter R Witschey; Zhaoyang Fan Journal: J Neuroimaging Date: 2020-05-11 Impact factor: 2.486