Matanelle Salama1, Ziva Amitai1, Nutman Amir2, Tamar Gottesman-Yekutieli3, Hilda Sherbany4, Yaron Drori4, Ella Mendelson5, Yehuda Carmeli2, Michal Mandelboim6. 1. Tel Aviv District Health Office, Ministry of Health, Tel Aviv, Israel. 2. Division of Epidemiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel. 3. Infectious Diseases Unit, Wolfson Medical Center, Holon, Israel. 4. Central Virology Laboratory, Ministry of Health, Chaim Sheba Medical Center, Ramat-Gan, Israel. 5. Central Virology Laboratory, Ministry of Health, Chaim Sheba Medical Center, Ramat-Gan, Israel; Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. 6. Central Virology Laboratory, Ministry of Health, Chaim Sheba Medical Center, Ramat-Gan, Israel. Electronic address: michalman@sheba.health.gov.il.
Abstract
BACKGROUND: Different types of adenoviruses are associated with diverse diseases and with varied disease severity. Adenovirus 55 could be associated with severe respiratory infections. OBJECTIVES: Here, we report on an adenovirus 55 outbreak in two psychiatric institutions in Israel. The objective of this study was to investigate the adenovirus 55 outbreak. STUDY DESIGN: We studied the clinical parameters of the patients and sequencing analysis of certain parts of the virus gene was performed. RESULTS: We identified the first patient who developed symptoms (the index case) and we showed that while both patients and staff members of the institutions were infected, the disease in the psychiatric patients was more severe. We attributed these differences to their mental and underlying health conditions. CONCLUSIONS: It is important to monitor for adenovirus infection in the community, especially in mental health institutions to allow appropriate medical care.
BACKGROUND: Different types of adenoviruses are associated with diverse diseases and with varied disease severity. Adenovirus 55 could be associated with severe respiratory infections. OBJECTIVES: Here, we report on an adenovirus 55 outbreak in two psychiatric institutions in Israel. The objective of this study was to investigate the adenovirus 55 outbreak. STUDY DESIGN: We studied the clinical parameters of the patients and sequencing analysis of certain parts of the virus gene was performed. RESULTS: We identified the first patient who developed symptoms (the index case) and we showed that while both patients and staff members of the institutions were infected, the disease in the psychiatricpatients was more severe. We attributed these differences to their mental and underlying health conditions. CONCLUSIONS: It is important to monitor for adenovirus infection in the community, especially in mental health institutions to allow appropriate medical care.
Authors: Ashrafali Mohamed Ismail; Xiaohong Zhou; David W Dyer; Donald Seto; Jaya Rajaiya; James Chodosh Journal: FEBS Lett Date: 2019-12-11 Impact factor: 4.124
Authors: Shoaleh Dehghan; Jason Seto; Elizabeth B Liu; Ashrafali M Ismail; Ramana Madupu; Albert Heim; Morris S Jones; David W Dyer; James Chodosh; Donald Seto Journal: J Virol Date: 2019-08-28 Impact factor: 5.103