Literature DB >> 26970165

Treatment as diagnosis and diagnosis as treatment: empirical management of presumptive tuberculosis in India.

A McDowell1, M Pai1.   

Abstract

BACKGROUND: Mismanagement of TB is a concern in the Indian private sector, and empirical management might be a key contributor.
OBJECTIVE: To understand factors associated with empirical diagnosis and treatment of presumed TB in India's private sector and examine their effects on TB care.
DESIGN: In this ethnographic study, 110 private practitioners of varying qualification who interacted with TB patients (90 in Mumbai and 20 in Patna) were interviewed, and a subset was observed while providing clinical care. Interviews and observations were analysed for indicators of empirical diagnosis and treatment.
RESULTS: All non-specialist practitioners began antibiotic treatment, especially quinolones, for persistent cough before prescribing a test. Several factors contribute to empirical management. These include a common practice use of medications as diagnostic tools, a desire to provide rapid symptom relief to patients, a desire to manage illness costs effectively, uncertainty about the presentation of TB, the effects of broad spectrum antibiotics on TB symptomology, and uncertainty about the accuracy of available TB tests.
CONCLUSION: Empiricism in general and in TB care is widespread in the urban private sector in India. Ethnography might offer useful insights for addressing this in public-private mix models.

Entities:  

Mesh:

Year:  2016        PMID: 26970165     DOI: 10.5588/ijtld.15.0562

Source DB:  PubMed          Journal:  Int J Tuberc Lung Dis        ISSN: 1027-3719            Impact factor:   2.373


  29 in total

Review 1.  TB control: challenges and opportunities for India.

Authors:  Madhukar Pai; Amrita Daftary; Srinath Satyanarayana
Journal:  Trans R Soc Trop Med Hyg       Date:  2016-03       Impact factor: 2.184

2.  Alternative medicine: an ethnographic study of how practitioners of Indian medical systems manage TB in Mumbai.

Authors:  Andrew McDowell; Madhukar Pai
Journal:  Trans R Soc Trop Med Hyg       Date:  2016-03       Impact factor: 2.184

3.  A List To Cement the Rightful Place of Diagnostics in Health Care.

Authors:  Lee F Schroeder; Madhukar Pai
Journal:  J Clin Microbiol       Date:  2018-09-25       Impact factor: 5.948

4.  Evaluating clinicians' user experience and acceptability of LearnTB, a smartphone application for tuberculosis in India.

Authors:  Tripti Pande; Kavitha Saravu; Zelalem Temesgen; Al Seyoum; Shipra Rai; Raghavendra Rao; Deekshith Mahadev; Madhukar Pai; Marie-Pierre Gagnon
Journal:  Mhealth       Date:  2017-07-27

5.  Tuberculosis diagnosis and management in the public versus private sector: a standardised patients study in Mumbai, India.

Authors:  Jishnu Das; Madhukar Pai; Benjamin Daniels; Daksha Shah; Ada T Kwan; Ranendra Das; Veena Das; Varsha Puri; Pranita Tipre; Upalimitra Waghmare; Mangala Gomare; Padmaja Keskar
Journal:  BMJ Glob Health       Date:  2022-10

Review 6.  Rapid molecular tests for tuberculosis and tuberculosis drug resistance: a qualitative evidence synthesis of recipient and provider views.

Authors:  Nora Engel; Eleanor A Ochodo; Perpetua Wanjiku Karanja; Bey-Marrié Schmidt; Ricky Janssen; Karen R Steingart; Sandy Oliver
Journal:  Cochrane Database Syst Rev       Date:  2022-04-26

7.  Urine lipoarabinomannan (LAM) and antimicrobial usage in seriously-ill HIV-infected patients with sputum smear-negative pulmonary tuberculosis.

Authors:  Thuli Mthiyane; Jonny Peter; Jenny Allen; Cathy Connolly; Malika Davids; Roxana Rustomjee; Timothy H Holtz; Lesibana Malinga; Keertan Dheda
Journal:  J Thorac Dis       Date:  2019-08       Impact factor: 2.895

8.  India's plan to eliminate tuberculosis by 2025: converting rhetoric into reality.

Authors:  Madhukar Pai; Soumyadeep Bhaumik; Soumitra S Bhuyan
Journal:  BMJ Glob Health       Date:  2017-03-20

9.  India's fight against tuberculosis: How can chest physicians help?

Authors:  Madhukar Pai; Parvaiz Koul
Journal:  Lung India       Date:  2017 Mar-Apr

10.  The effect of empirical and laboratory-confirmed tuberculosis on treatment outcomes.

Authors:  Osman Abdullahi; Ngari Moses; Deche Sanga; Willetts Annie
Journal:  Sci Rep       Date:  2021-07-21       Impact factor: 4.379

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