| Literature DB >> 26963582 |
Lu Liu1,2, Chang-Wei Song1, Afsar Khan1,3, Xiao-Ning Li1, Xing-Wei Yang1, Gui-Guang Cheng1, Ya-Ping Liu1, Xiao-Dong Luo1.
Abstract
A new strychnine alkaloid, 16,17,19,20-tetrahydro-2,16-dehydro-18-deoxyisostrychnine (1), and fourteen known alkaloids were isolated from the leaves of Psychotria pilifera. Their structures were identified on the basis of extensive spectroscopic analysis, as well as by comparison with the reported spectroscopic data. The new alkaloid (1) exhibited potent antibacterial activity against Escherichia coli, equivalent to cefotaxime with MIC value of 0.781 μg/ml.Entities:
Keywords: 16,17,19,20–tetrahydro–2,16–dehydro–18–deoxyisostrychnine; Psychotria pilifera; Rubiaceae; antibacterial activity; indole alkaloid
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Year: 2016 PMID： 26963582 DOI： 10.1080/10286020.2016.1158710
Source DB: PubMed Journal: J Asian Nat Prod Res ISSN： 1028-6020 Impact factor: 1.569