| Literature DB >> 26959614 |
Deepak Kumar1, Ashish Gupta1, Kavindra Nath2.
Abstract
Advances in the application of NMR spectroscopy-based metabolomic profiling of prostate cancer comprises a potential tactic for understanding the impaired biochemical pathways arising due to a disease evolvement and progression. This technique involves qualitative and quantitative estimation of plethora of small molecular weight metabolites of body fluids or tissues using state-of-the-art chemometric methods delivering an important platform for translational research from basic to clinical, to reveal the pathophysiological snapshot in a single step. This review summarizes the present arrays and recent advancements in NMR-based metabolomics and a glimpse of currently used medical imaging tactics, with their role in clinical diagnosis of prostate cancer.Entities:
Keywords: MRSI; Metabolomics; NMR spectroscopy; PET; clinical intervention; prostate cancer
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Year: 2016 PMID: 26959614 DOI: 10.1586/14737159.2016.1164037
Source DB: PubMed Journal: Expert Rev Mol Diagn ISSN: 1473-7159 Impact factor: 5.225