Literature DB >> 26949370

Concise Synthesis of Tetrazole-keto-piperazines by Two Consecutive Ugi Reactions.

Tryfon Zarganes-Tzitzikas1, Pravin Patil1, Kareem Khoury2, Eberhardt Herdtweck3, Alexander Dömling1.   

Abstract

Entities:  

Year:  2014        PMID： 26949370      PMCID： PMC4774864          DOI： 10.1002/ejoc.201403401

Source DB:  PubMed          Journal:  European J Org Chem        ISSN： 1099-0690


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  11 in total

1.  Molecular shape diversity of combinatorial libraries: a prerequisite for broad bioactivity.

Authors:  Wolfgang H B Sauer; Matthias K Schwarz
Journal:  J Chem Inf Comput Sci       Date:  2003 May-Jun

Review 2.  Isocyanoacetate derivatives: synthesis, reactivity, and application.

Authors:  Anton V Gulevich; Alexander G Zhdanko; Romano V A Orru; Valentine G Nenajdenko
Journal:  Chem Rev       Date:  2010-09-08       Impact factor: 60.622

3.  ZINC--a free database of commercially available compounds for virtual screening.

Authors:  John J Irwin; Brian K Shoichet
Journal:  J Chem Inf Model       Date:  2005 Jan-Feb       Impact factor: 4.956

Review 4.  2,5-Diketopiperazines: synthesis, reactions, medicinal chemistry, and bioactive natural products.

Authors:  Alan D Borthwick
Journal:  Chem Rev       Date:  2012-05-11       Impact factor: 60.622

5.  The efficient one-pot reaction of up to eight components by the union of multicomponent reactions.

Authors:  Niels Elders; Dion van der Born; Loes J D Hendrickx; Brian J J Timmer; Alrik Krause; Elwin Janssen; Frans J J de Kanter; Eelco Ruijter; Romano V A Orru
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

6.  Identification of highly selective inhibitors of collagenase-1 from combinatorial libraries of diketopiperazines.

Authors:  A K Szardenings; V Antonenko; D A Campbell; N DeFrancisco; S Ida; L Shi; N Sharkov; D Tien; Y Wang; M Navre
Journal:  J Med Chem       Date:  1999-04-22       Impact factor: 7.446

7.  Pyridyl-2,5-diketopiperazines as potent, selective, and orally bioavailable oxytocin antagonists: synthesis, pharmacokinetics, and in vivo potency.

Authors:  Alan D Borthwick; John Liddle; Dave E Davies; Anne M Exall; Christopher Hamlett; Deirdre M Hickey; Andrew M Mason; Ian E D Smith; Fabrizio Nerozzi; Simon Peace; Derek Pollard; Steve L Sollis; Michael J Allen; Patrick M Woollard; Mark A Pullen; Timothy D Westfall; Dinesh J Stanislaus
Journal:  J Med Chem       Date:  2012-01-12       Impact factor: 7.446

8.  Parallel synthesis of arrays of amino-acid-derived isocyanoamides useful as starting materials in IMCR.

Authors:  Alexander Dömling; Barbara Beck; Thilo Fuchs; Ahmad Yazbak
Journal:  J Comb Chem       Date:  2006 Nov-Dec

9.  Access to indole- and pyrrole-fused diketopiperazines via tandem Ugi-4CR/intramolecular cyclization and its regioselective ring-opening by intermolecular transamidation.

Authors:  Shashi Pandey; Shahnawaz Khan; Awantika Singh; Harsh M Gauniyal; Brijesh Kumar; Prem M S Chauhan
Journal:  J Org Chem       Date:  2012-10-25       Impact factor: 4.354

10.  Tritylamine as an ammonia surrogate in the Ugi tetrazole synthesis.

Authors:  Ting Zhao; André Boltjes; Eberhardt Herdtweck; Alexander Dömling
Journal:  Org Lett       Date:  2013-01-18       Impact factor: 6.005
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  8 in total

Review 1.  Groebke-Blackburn-Bienaymé multicomponent reaction: emerging chemistry for drug discovery.

Authors:  Saad Shaaban; Bakr F Abdel-Wahab
Journal:  Mol Divers       Date:  2015-05-28       Impact factor: 2.943

Review 2.  Tetrazoles via Multicomponent Reactions.

Authors:  Constantinos G Neochoritis; Ting Zhao; Alexander Dömling
Journal:  Chem Rev       Date:  2019-02-01       Impact factor: 60.622

3.  α-Amino Acid-Isosteric α-Amino Tetrazoles.

Authors:  Ting Zhao; Katarzyna Kurpiewska; Justyna Kalinowska-Tłuścik; Eberhardt Herdtweck; Alexander Dömling
Journal:  Chemistry       Date:  2016-01-28       Impact factor: 5.236

4.  Ammonia-Promoted One-Pot Tetrazolopiperidinone Synthesis by Ugi Reaction.

Authors:  Pravin Patil; Katarzyna Kurpiewska; Justyna Kalinowska-Tłuścik; Alexander Dömling
Journal:  ACS Comb Sci       Date:  2017-03-08       Impact factor: 3.784

5.  Synthesis of acylhydrazino-peptomers, a new class of peptidomimetics, by consecutive Ugi and hydrazino-Ugi reactions.

Authors:  Angélica de Fátima S Barreto; Veronica Alves Dos Santos; Carlos Kleber Z Andrade
Journal:  Beilstein J Org Chem       Date:  2016-12-27       Impact factor: 2.883

6.  Application of Silver Nanoparticles in the Multicomponent Reaction Domain: A Combined Catalytic Reduction Methodology to Efficiently Access Potential Hypertension or Inflammation Inhibitors.

Authors:  Domna Iordanidou; Tryfon Zarganes-Tzitzikas; Constantinos G Neochoritis; Alexander Dömling; Ioannis N Lykakis
Journal:  ACS Omega       Date:  2018-11-27

7.  Supported Gold Nanoparticle-Catalyzed Selective Reduction of Multifunctional, Aromatic Nitro Precursors into Amines and Synthesis of 3,4-Dihydroquinoxalin-2-Ones.

Authors:  Domna Iordanidou; Michael G Kallitsakis; Marina A Tzani; Dimitris I Ioannou; Tryfon Zarganes-Tzitzikas; Constantinos G Neochoritis; Alexander Dömling; Michael A Terzidis; Ioannis N Lykakis
Journal:  Molecules       Date:  2022-07-08       Impact factor: 4.927

8.  Two Cycles with One Catch: Hydrazine in Ugi 4-CR and Its Postcyclizations.

Authors:  Yuanze Wang; Pravin Patil; Katarzyna Kurpiewska; Justyna Kalinowska-Tluscik; Alexander Dömling
Journal:  ACS Comb Sci       Date:  2017-02-17       Impact factor: 3.784
  8 in total

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