Literature DB >> 22575049

2,5-Diketopiperazines: synthesis, reactions, medicinal chemistry, and bioactive natural products.

Alan D Borthwick1.   

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Year:  2012        PMID: 22575049     DOI: 10.1021/cr200398y

Source DB:  PubMed          Journal:  Chem Rev        ISSN: 0009-2665            Impact factor:   60.622


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  145 in total

1.  Concise Total Synthesis of (+)-Asperazine, (+)-Pestalazine A, and (+)-iso-Pestalazine A. Structure Revision of (+)-Pestalazine A.

Authors:  Richard P Loach; Owen S Fenton; Mohammad Movassaghi
Journal:  J Am Chem Soc       Date:  2016-01-19       Impact factor: 15.419

Review 2.  Strategies for the Optimization of Natural Leads to Anticancer Drugs or Drug Candidates.

Authors:  Zhiyan Xiao; Susan L Morris-Natschke; Kuo-Hsiung Lee
Journal:  Med Res Rev       Date:  2015-09-11       Impact factor: 12.944

3.  New diketopiperazine derivatives with cytotoxicity from Nocardiopsis sp. YIM M13066.

Authors:  Mingwei Sun; Xiaotong Chen; Wenjun Li; Chunhua Lu; Yuemao Shen
Journal:  J Antibiot (Tokyo)       Date:  2017-04-05       Impact factor: 2.649

4.  Synthesis and biological evaluation of epidithio-, epitetrathio-, and bis-(methylthio)diketopiperazines: synthetic methodology, enantioselective total synthesis of epicoccin G, 8,8'-epi-ent-rostratin B, gliotoxin, gliotoxin G, emethallicin E, and haematocin and discovery of new antiviral and antimalarial agents.

Authors:  K C Nicolaou; Min Lu; Sotirios Totokotsopoulos; Philipp Heretsch; Denis Giguère; Ya-Ping Sun; David Sarlah; Thu H Nguyen; Ian C Wolf; Donald F Smee; Craig W Day; Selina Bopp; Elizabeth A Winzeler
Journal:  J Am Chem Soc       Date:  2012-10-04       Impact factor: 15.419

5.  n→π* Interactions Modulate the Disulfide Reduction Potential of Epidithiodiketopiperazines.

Authors:  Henry R Kilgore; Chase R Olsson; Kyan A D'Angelo; Mohammad Movassaghi; Ronald T Raines
Journal:  J Am Chem Soc       Date:  2020-08-21       Impact factor: 15.419

6.  A Modular Construction of Epidithiodiketopiperazines.

Authors:  Thomas N Snaddon; Toya D Scaggs; Colin M Pearson; James W B Fyfe
Journal:  Org Lett       Date:  2019-06-11       Impact factor: 6.005

7.  Cyclic cis-Locked Phospho-Dipeptides Reduce Entry of AβPP into Amyloidogenic Processing Pathway.

Authors:  Carolyn L Fisher; Ross J Resnick; Soumya De; Lucila A Acevedo; Kun Ping Lu; Frank C Schroeder; Linda K Nicholson
Journal:  J Alzheimers Dis       Date:  2017       Impact factor: 4.472

8.  General approach for preparing epidithiodioxopiperazines from trioxopiperazine precursors: enantioselective total syntheses of (+)- and (-)-gliocladine C, (+)-leptosin D, (+)-T988C, (+)-bionectin A, and (+)-gliocladin A.

Authors:  John E DeLorbe; David Horne; Richard Jove; Steven M Mennen; Sangkil Nam; Fang-Li Zhang; Larry E Overman
Journal:  J Am Chem Soc       Date:  2013-03-01       Impact factor: 15.419

9.  A Promiscuous Cytochrome P450 Hydroxylates Aliphatic and Aromatic C-H Bonds of Aromatic 2,5-Diketopiperazines.

Authors:  Guangde Jiang; Yi Zhang; Magan M Powell; Sarah M Hylton; Nicholas W Hiller; Rosemary Loria; Yousong Ding
Journal:  Chembiochem       Date:  2019-03-27       Impact factor: 3.164

10.  A microbial metabolite synergizes with endogenous serotonin to trigger C. elegans reproductive behavior.

Authors:  Yen-Chih Chen; Mohammad R Seyedsayamdost; Niels Ringstad
Journal:  Proc Natl Acad Sci U S A       Date:  2020-11-16       Impact factor: 11.205

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