Wendee M Wechsberg1, William A Zule2, Nabila El-Bassel3, Irene A Doherty4, Alexandra M Minnis5, Scott D Novak2, Bronwyn Myers6, Tara Carney7. 1. RTI International, 3040 East Cornwallis Road, Research Triangle Park, NC, United States; University of North Carolina, Chapel Hill, NC, United States; Department of Psychology in the Public Interest, North Carolina State University, Raleigh, NC, United States; Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, United States. Electronic address: wmw@rti.org. 2. RTI International, 3040 East Cornwallis Road, Research Triangle Park, NC, United States. 3. Columbia University School of Social Work, New York, NY, United States. 4. RTI International, 3040 East Cornwallis Road, Research Triangle Park, NC, United States; University of North Carolina, Chapel Hill, NC, United States. 5. RTI International, 351 California Street, San Francisco, CA, United States. 6. Alcohol, Tobacco & Other Drug Research Unit, South African Medical Research Council, Cape Town, South Africa; Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa. 7. Alcohol, Tobacco & Other Drug Research Unit, South African Medical Research Council, Cape Town, South Africa.
Abstract
BACKGROUND: This study examined the effects of the Couples Health CoOp intervention on heavy drinking, condom use, and HIV incidence. METHODS:Thirty neighborhoods from one South African township were cluster randomized into three intervention arms: Couples Health CoOp (CHC), Women's Health CoOp/Men's Health CoOp (WHC/MHC), or a comparison arm. We recruited 290 men from informal drinking establishments who reported drinking alcohol regularly. We also recruited their main heterosexual sex partners. RESULTS: At 6-month follow-up, men in the CHC arm were less likely to report heavy drinking (OR 0.47, 95% CI: 0.25, 0.90) and were more likely to report consistent condom use during the past month (OR 2.66, 95% CI: 1.23, 5.76) than men in the comparison arm. At baseline, 26% of women and 13% of men were HIV-infected; at 6-month follow-up, 16 females and 5 males had seroconverted. HIV incidence was significantly lower among women in the CHC arm (IRR 0.22, 95% CI: 0.04, 1.01) than in the WHC/MHC arm. CONCLUSIONS: A couples-based intervention focusing on intersecting risks for HIV can improve biobehavioral outcomes, underscoring the importance of engaging couples together in HIV prevention.
RCT Entities:
BACKGROUND: This study examined the effects of the Couples Health CoOp intervention on heavy drinking, condom use, and HIV incidence. METHODS: Thirty neighborhoods from one South African township were cluster randomized into three intervention arms: Couples Health CoOp (CHC), Women's Health CoOp/Men's Health CoOp (WHC/MHC), or a comparison arm. We recruited 290 men from informal drinking establishments who reported drinking alcohol regularly. We also recruited their main heterosexual sex partners. RESULTS: At 6-month follow-up, men in the CHC arm were less likely to report heavy drinking (OR 0.47, 95% CI: 0.25, 0.90) and were more likely to report consistent condom use during the past month (OR 2.66, 95% CI: 1.23, 5.76) than men in the comparison arm. At baseline, 26% of women and 13% of men were HIV-infected; at 6-month follow-up, 16 females and 5 males had seroconverted. HIV incidence was significantly lower among women in the CHC arm (IRR 0.22, 95% CI: 0.04, 1.01) than in the WHC/MHC arm. CONCLUSIONS: A couples-based intervention focusing on intersecting risks for HIV can improve biobehavioral outcomes, underscoring the importance of engaging couples together in HIV prevention.
Authors: Quarraisha Abdool Karim; Salim S Abdool Karim; Janet A Frohlich; Anneke C Grobler; Cheryl Baxter; Leila E Mansoor; Ayesha B M Kharsany; Sengeziwe Sibeko; Koleka P Mlisana; Zaheen Omar; Tanuja N Gengiah; Silvia Maarschalk; Natasha Arulappan; Mukelisiwe Mlotshwa; Lynn Morris; Douglas Taylor Journal: Science Date: 2010-07-19 Impact factor: 47.728
Authors: Susan Allen; Jareen Meinzen-Derr; Michele Kautzman; Isaac Zulu; Stanley Trask; Ulgen Fideli; Rosemary Musonda; Francis Kasolo; Feng Gao; Alan Haworth Journal: AIDS Date: 2003-03-28 Impact factor: 4.177
Authors: Wendee M Wechsberg; Irene A Doherty; Bronwyn Myers; Antonio A Morgan-Lopez; Andrea Emanuel; Tara Carney; Tracy L Kline; William A Zule Journal: Int J Drug Policy Date: 2013-11-09
Authors: Jared M Baeten; Deborah Donnell; Patrick Ndase; Nelly R Mugo; James D Campbell; Jonathan Wangisi; Jordan W Tappero; Elizabeth A Bukusi; Craig R Cohen; Elly Katabira; Allan Ronald; Elioda Tumwesigye; Edwin Were; Kenneth H Fife; James Kiarie; Carey Farquhar; Grace John-Stewart; Aloysious Kakia; Josephine Odoyo; Akasiima Mucunguzi; Edith Nakku-Joloba; Rogers Twesigye; Kenneth Ngure; Cosmas Apaka; Harrison Tamooh; Fridah Gabona; Andrew Mujugira; Dana Panteleeff; Katherine K Thomas; Lara Kidoguchi; Meighan Krows; Jennifer Revall; Susan Morrison; Harald Haugen; Mira Emmanuel-Ogier; Lisa Ondrejcek; Robert W Coombs; Lisa Frenkel; Craig Hendrix; Namandjé N Bumpus; David Bangsberg; Jessica E Haberer; Wendy S Stevens; Jairam R Lingappa; Connie Celum Journal: N Engl J Med Date: 2012-07-11 Impact factor: 91.245
Authors: Wendee M Wechsberg; Rachel Jewkes; Scott P Novak; Tracy Kline; Bronwyn Myers; Felicia A Browne; Tara Carney; Antonio A Morgan Lopez; Charles Parry Journal: BMJ Open Date: 2013-05-28 Impact factor: 2.692
Authors: Alexandra M Minnis; Irene A Doherty; Tracy L Kline; William A Zule; Bronwyn Myers; Tara Carney; Wendee M Wechsberg Journal: Int J Womens Health Date: 2015-05-11
Authors: Wenhao Dai; Ryan Palmer; Aashna Sunderrajan; Marta Durantini; Flor Sánchez; Laura R Glasman; Fan Xuan Chen; Dolores Albarracín Journal: Psychol Addict Behav Date: 2020-04-20
Authors: Jennifer M Belus; Alexandra L Rose; Lena S Andersen; Nonceba Ciya; John A Joska; Bronwyn Myers; Steven A Safren; Jessica F Magidson Journal: Cogn Behav Pract Date: 2020-11-10
Authors: Alexandra L Rose; Jennifer M Belus; Tianzhou Ma; Jasper S Lee; Christine Wan; Andres De Los Reyes; John A Joska; Lena S Andersen; Bronwyn Myers; Jessica F Magidson Journal: AIDS Behav Date: 2022-01-13
Authors: Wendee M Wechsberg; Felicia A Browne; Jacqueline Ndirangu; Courtney Peasant Bonner; Alexandra M Minnis; Laura Nyblade; Ilene S Speizer; Brittni N Howard; Bronwyn Myers; Khatija Ahmed Journal: BMC Public Health Date: 2020-09-15 Impact factor: 3.295