Literature DB >> 26942725

Healthcare Cost of Over-Diagnosis of Low-Grade Dysplasia in Barrett's Esophagus.

Richard H Lash1, Thomas M Deas2, Frank H Wians3.   

Abstract

INTRODUCTION: Published reports have demonstrated that many Barrett's esophagus patients are over-diagnosed as low-grade dysplasia (BE-LGD). We performed an analysis of the surveillance and treatment costs associated with the over-diagnosis of BE-LGD.
METHODS: As the principal cost variables, we used endoscopic and histologic procedures performed during the recommended surveillance intervals for patients with BE-LGD, the national average Medicare reimbursement for the Current Procedural Terminology codes of the procedures performed, and a spreadsheet-based tool we created to determine the overall healthcare cost associated with the over-diagnosis of BE-LGD in the US population.
RESULTS: The average excess cost (range) for every patient in the US who is over-diagnosed with BE-LGD is estimated to be $5557 ($3115 to $8072). The principal contributors to the excess cost of over-diagnosis of BE-LGD in these patients are: endoscopy ($2626 to $4639), pathologist biopsy review ($275 to $2185), and esophagogastroduodenoscopy-guided endoscopic ablation ($214 to $1249).
CONCLUSIONS: The healthcare cost of over-diagnosis of BE-LGD is significant. To reduce the overall healthcare cost impact of over-diagnosis of BE-LGD, strict adherence to the recommendations of the American Gastroenterological Association, American College of Gastroenterology, and American Society for Gastrointestinal Endoscopy that pathology review of all BE biopsy specimens be performed by a gastrointestinal pathologist is warranted.

Entities:  

Keywords:  Barrett’s esophagus; Endoscopic surveillance; Health economic impact; Low-grade dysplasia; Over-diagnosis

Mesh:

Year:  2016        PMID: 26942725     DOI: 10.1007/s12325-016-0308-7

Source DB:  PubMed          Journal:  Adv Ther        ISSN: 0741-238X            Impact factor:   3.845


  4 in total

1.  Establishing funding rates for colonoscopy and gastroscopy procedures in Ontario.

Authors:  J Monakova; J Wong; I Blais; A Langan; N Ratansi; D Morgan; N N Baxter
Journal:  Curr Oncol       Date:  2019-04-01       Impact factor: 3.677

2.  Detection of Mutations in Barrett's Esophagus Before Progression to High-Grade Dysplasia or Adenocarcinoma.

Authors:  Matthew D Stachler; Nicholas D Camarda; Christopher Deitrick; Anthony Kim; Agoston T Agoston; Robert D Odze; Jason L Hornick; Anwesha Nag; Aaron R Thorner; Matthew Ducar; Amy Noffsinger; Richard H Lash; Mark Redston; Scott L Carter; Jon M Davison; Adam J Bass
Journal:  Gastroenterology       Date:  2018-03-31       Impact factor: 22.682

3.  TissueCypher Barrett's esophagus assay impacts clinical decisions in the management of patients with Barrett's esophagus.

Authors:  David L Diehl; Harshit S Khara; Nasir Akhtar; Rebecca J Critchley-Thorne
Journal:  Endosc Int Open       Date:  2021-02-18

4.  Abnormal TP53 Predicts Risk of Progression in Patients With Barrett's Esophagus Regardless of a Diagnosis of Dysplasia.

Authors:  Mark Redston; Amy Noffsinger; Anthony Kim; Fahire G Akarca; Marianne Rara; Diane Stapleton; Laurel Nowden; Richard Lash; Adam J Bass; Matthew D Stachler
Journal:  Gastroenterology       Date:  2021-10-29       Impact factor: 33.883

  4 in total

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