Literature DB >> 26942050

The role of NF-kB in modulating antitumor immunity.

Ann Richmond1, Jinming Yang1.   

Abstract

Recent breakthroughs in therapeutic modulation of immune cells have led to novel exciting treatments for cancers. Moreover, the cytokine milieu in the tumor microenvironment is important for appropriate immune surveillance. Here, we demonstrate that NF-κB activity in myeloid cells is essential for cytokine-mediated antitumor polarization of immune cells.

Entities:  

Keywords:  NF-κB; T cells; cytokines; melanoma; myeloid cells; tumor-associated macrophages

Year:  2015        PMID： 26942050      PMCID： PMC4760307          DOI： 10.1080/2162402X.2015.1005522

Source DB:  PubMed          Journal:  Oncoimmunology        ISSN： 2162-4011            Impact factor:   8.110


  10 in total

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2.  Tumor entrained neutrophils inhibit seeding in the premetastatic lung.

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Review 3.  Coordinated regulation of myeloid cells by tumours.

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4.  Myeloid IKKβ promotes antitumor immunity by modulating CCL11 and the innate immune response.

Authors:  Jinming Yang; Oriana E Hawkins; Whitney Barham; Pavlo Gilchuk; Mark Boothby; Gregory D Ayers; Sebastian Joyce; Michael Karin; Fiona E Yull; Ann Richmond
Journal:  Cancer Res       Date:  2014-10-21       Impact factor: 12.701

5.  The cellular and molecular origin of tumor-associated macrophages.

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7.  CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages.

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Review 8.  Tumor-associated macrophages: from mechanisms to therapy.

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  10 in total
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Review 5.  Flavonoids as Cytokine Modulators: A Possible Therapy for Inflammation-Related Diseases.

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Review 6.  MicroRNA Roles in the Nuclear Factor Kappa B Signaling Pathway in Cancer.

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  6 in total

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