Literature DB >> 26941051

The influence of bone mineral density and bisphosphonate therapy on the determinants of oral health and changes on dental panoramic radiographs in postmenopausal women.

Olja Grgić1, Branka Kovačev-Zavišić2, Tanja Veljović1, Jovanka Novaković-Paro2, Tatjana Maravić1, Branislav Bajkin3.   

Abstract

OBJECTIVES: The aim of this study was to assess the determinants of oral health including the number of decayed, missing, and filled teeth (DMFT) and periodontal indices in postmenopausal women with osteoporosis, osteoporosis treated with bisphosphonate therapy, and control group and to examine the correlation between dental panoramic indices (Mental Index-MI, Mandibular Cortical Index-MCI) and bone mineral density in these three groups of patients.
MATERIALS AND METHODS: The presented non-interventional study involved 120 postmenopausal women: women with osteoporosis (O) (n = 45), women with osteoporosis treated with bisphosphonates (OBP) (n = 45), and control group (C) (n = 30). DMFT, plaque, gingival and papilla bleeding index, pocket depth, clinical attachment loss, and the presence of periodontitis were evaluated for each patient. MI and MCI of all participants were measured on a dental panoramic radiograph.
RESULTS: Group OBP showed significantly higher gingival, bleeding index and deeper pocket depth than C and/or O group. No significant differences were found in MI (p = .303) or MCI (p = .06) in all the examined groups. Also, there were no significant differences between the three groups in the presence of periodontitis as well as in the DMFT index.
CONCLUSION: BP therapy could have a negative influence on periodontal health. Further, MI and MCI are not precise diagnostic tools for diagnosing low BMD in postmenopausal women. CLINICAL RELEVANCE: BP therapy could have a negative influence on the determinants of oral health in postmenopausal women with osteoporosis.

Entities:  

Keywords:  Bisphosphonates; Dental panoramic radiograph; Oral health; Osteoporosis

Mesh:

Substances:

Year:  2016        PMID: 26941051     DOI: 10.1007/s00784-016-1767-6

Source DB:  PubMed          Journal:  Clin Oral Investig        ISSN: 1432-6981            Impact factor:   3.573


  41 in total

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2.  The influence of bisphosphonates on viability, migration, and apoptosis of human oral keratinocytes--in vitro study.

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3.  The association between bone mineral density and periodontitis in Korean adults (KNHANES 2008-2010).

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4.  Outcome measurements in studies on the association between osteoporosis and periodontal disease.

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6.  Influence of bisphosphonates on endothelial cells, fibroblasts, and osteogenic cells.

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Review 7.  Triage screening for osteoporosis in dental clinics using panoramic radiographs.

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Review 9.  Osteoporosis, jawbones and periodontal disease.

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10.  European guidance for the diagnosis and management of osteoporosis in postmenopausal women.

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Journal:  Osteoporos Int       Date:  2012-10-19       Impact factor: 4.507

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Review 2.  Comorbidity of periodontal disease: two sides of the same coin? An introduction for the clinician.

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3.  Factors Associated with Tooth Loss in Postmenopausal Women: A Community-Based Cross-Sectional Study.

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