| Literature DB >> 26932442 |
Claudia Filippone1, Guillaume Castel2, Séverine Murri3, Frédérik Beaulieux4, Myriam Ermonval1, Corinne Jallet1, Emma L Wise5, Richard J Ellis5, Denise A Marston5, Lorraine M McElhinney5,6, Anthony R Fooks5,6, Amélie Desvars7, Lénaı G Halos8, Gwenaël Vourc'h7, Philippe Marianneau3, Noël Tordo1.
Abstract
Hantaviruses are emerging zoonotic viruses that cause human diseases. In this study, sera from 642 mammals from La Réunion and Mayotte islands (Indian Ocean) were screened for the presence of hantaviruses by molecular analysis. None of the mammals from La Réunion island was positive, but hantavirus genomic RNA was discovered in 29/160 (18 %) Rattus rattus from Mayotte island. The nucleoprotein coding region was sequenced from the liver and spleen of all positive individuals allowing epidemiological and intra-strain variability analyses. Phylogenetic analysis based on complete coding genomic sequences showed that this Murinae-associated hantavirus is a new variant of Thailand virus. Further studies are needed to investigate hantaviruses in rodent hosts and in Haemorrhagic Fever with Renal Syndrome (HFRS) human cases.Entities:
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Year: 2016 PMID： 26932442 PMCID： PMC4851257 DOI： 10.1099/jgv.0.000440
Source DB: PubMed Journal: J Gen Virol ISSN： 0022-1317 Impact factor: 3.891