Literature DB >> 26929457

Locally advanced hypopharyngeal squamous cell carcinoma: single-institution outcomes in a cohort of patients curatively treated either with or without larynx preservation.

Isabel Reis1, Artur Aguiar1, Cristiana Alzamora2, Carolina Ferreira2, Vera Castro1, André Soares1, Marisa Lobão1.   

Abstract

OBJECTIVE: The present study was aimed at describing a single-institution experience in the curative treatment of patients diagnosed with locally advanced hypopharyngeal squamous cell carcinoma.
MATERIALS AND METHODS: Data concerning all patients treated for locally advanced hypopharyngeal squamous cell carcinoma between January 2006 and June 2012 were reviewed.
RESULTS: A total of 144 patients were included in the present study. The median follow-up period was 36.6 months. Median survival was 26 months, and 2-year and 5-year overall survival rates were, 51% and 30.5%, respectively. Median recurrence-free survival was 18 months and 2-year and 5-year recurrence-free survival rates were 42.8% and 28.5%, respectively.
CONCLUSION: The outcomes in the present series are in line with the literature.

Entities:  

Keywords:  Hypopharynx; Outcomes; Radiotherapy; Surgery

Year:  2016        PMID: 26929457      PMCID: PMC4770393          DOI: 10.1590/0100-3984.2015.0018

Source DB:  PubMed          Journal:  Radiol Bras        ISSN: 0100-3984


  14 in total

1.  Advanced hypopharyngeal carcinoma treatment results according to treatment modalities.

Authors:  S Kim; H G Wu; D S Heo; K H Kim; M W Sung; C I Park
Journal:  Head Neck       Date:  2001-09       Impact factor: 3.147

2.  Evidence-based management of hypopharyngeal cancer.

Authors:  A Roboson
Journal:  Clin Otolaryngol Allied Sci       Date:  2002-10

3.  Larynx preservation in pyriform sinus cancer: preliminary results of a European Organization for Research and Treatment of Cancer phase III trial. EORTC Head and Neck Cancer Cooperative Group.

Authors:  J L Lefebvre; D Chevalier; B Luboinski; A Kirkpatrick; L Collette; T Sahmoud
Journal:  J Natl Cancer Inst       Date:  1996-07-03       Impact factor: 13.506

4.  Hyperfractionated accelerated chemoradiation with concurrent fluorouracil-mitomycin is more effective than dose-escalated hyperfractionated accelerated radiation therapy alone in locally advanced head and neck cancer: final results of the radiotherapy cooperative clinical trials group of the German Cancer Society 95-06 Prospective Randomized Trial.

Authors:  Volker Budach; Martin Stuschke; Wilfried Budach; Michael Baumann; Dirk Geismar; Gerhard Grabenbauer; Ingrid Lammert; Klaus Jahnke; Georg Stueben; Thomas Herrmann; Michael Bamberg; Peter Wust; Wolfgang Hinkelbein; Klaus-Dieter Wernecke
Journal:  J Clin Oncol       Date:  2005-02-20       Impact factor: 44.544

5.  Combined chemotherapy and radiotherapy versus surgery and postoperative radiotherapy for advanced hypopharyngeal cancer.

Authors:  M J Zelefsky; D H Kraus; D G Pfister; A Raben; J P Shah; E W Strong; R H Spiro; G J Bosl; L B Harrison
Journal:  Head Neck       Date:  1996 Sep-Oct       Impact factor: 3.147

6.  Radiochemotherapy versus surgery plus radio(chemo)therapy for stage T3/T4 larynx and hypopharynx cancer - results of a matched-pair analysis.

Authors:  Dirk Rades; Ursula Schroeder; Amira Bajrovic; Steven E Schild
Journal:  Eur J Cancer       Date:  2011-07-02       Impact factor: 9.162

7.  Hyperfractionated radiation therapy with or without concurrent low-dose daily cisplatin in locally advanced squamous cell carcinoma of the head and neck: a prospective randomized trial.

Authors:  B Jeremic; Y Shibamoto; B Milicic; N Nikolic; A Dagovic; J Aleksandrovic; Z Vaskovic; L Tadic
Journal:  J Clin Oncol       Date:  2000-04       Impact factor: 44.544

8.  A Radiation Therapy Oncology Group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: first report of RTOG 9003.

Authors:  K K Fu; T F Pajak; A Trotti; C U Jones; S A Spencer; T L Phillips; A S Garden; J A Ridge; J S Cooper; K K Ang
Journal:  Int J Radiat Oncol Biol Phys       Date:  2000-08-01       Impact factor: 7.038

9.  Radiation therapy with or without concurrent low-dose daily chemotherapy in locally advanced, nonmetastatic squamous cell carcinoma of the head and neck.

Authors:  Branislav Jeremic; Biljana Milicic; Aleksandar Dagovic; Zeljko Vaskovic; Ljiljana Tadic
Journal:  J Clin Oncol       Date:  2004-09-01       Impact factor: 44.544

10.  Definitive Radiotherapy versus Postoperative Radiotherapy of Patients with Oro- and Hypopharyngeal Cancer: Impact of Prognostic Factors.

Authors:  Volker Rudat; Salia Ahmet-Osman; Oliver Schramm; Andreas Dietz
Journal:  J Oncol       Date:  2012-01-18       Impact factor: 4.375

View more
  2 in total

1.  Poorly differentiated large-cell neuroendocrine carcinoma of the paranasal sinus.

Authors:  Helder Groenwold Campos; Albina Messias Altemani; João Altemani; Davi Ferreira Soares; Fabiano Reis
Journal:  Radiol Bras       Date:  2018 Jul-Aug

2.  The presence of risk factors and corresponding treatment strategies post-surgical resection in stage IV hypopharyngeal squamous cell carcinoma patients: a retrospective cohort study.

Authors:  Yu Heng; Xiaoke Zhu; Liang Zhou; Ming Zhang; Hong Zhou; Lei Tao
Journal:  Ann Transl Med       Date:  2020-03
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.