Literature DB >> 26923317

DrugCam®-An intelligent video camera system to make safe cytotoxic drug preparations.

Frédéric Benizri1, Benoit Dalifard2, Christophe Zemmour3, Maxime Henriquet4, Emmanuelle Fougereau4, Benoit Le Franc2.   

Abstract

DrugCam(®) is a new approach to control the chemotherapy preparations with an intelligent video system that enables automatic verification during the critical stages of preparations combined with an a posteriori control with partial or total visualization of the video recording of preparations. The assessment was about the recognizing of anticancer drug vials (qualitative analysis) and syringe volumes (quantitative analysis). The qualitative analysis was conducted for a total of 120 vials with sensitivity of 100% for 84.2% of the vials and at least 97% for all the vials tested. Accuracy was at least 98.5% for all vials. The quantitative analysis was assessed by detecting 10 measures of each graduation for syringes. The identification error rate was 2.1% (244/11,640) i.e. almost 94% to the next graduation. Only 3% (35/1164) of the graduations tested, i.e. 23/35 for volume <0.13 ml of 1 ml syringes, presented a volume error outside the admissible limit of ± 5% of a confidence band constructed for the estimated linear regression line for each syringe. In addition to the vial detection model, barcodes can also read when they are present on vials. DrugCam(®) offers an innovative approach for controlling chemotherapy preparations and constitutes an optimized application of telepharmacy.
Copyright © 2016 Elsevier B.V. All rights reserved.

Keywords:  Chemotherapies; Qualitative control; Quantitative control; Telepharmacy; Video camera

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Year:  2016        PMID: 26923317     DOI: 10.1016/j.ijpharm.2016.02.028

Source DB:  PubMed          Journal:  Int J Pharm        ISSN: 0378-5173            Impact factor:   5.875


  2 in total

1.  Quality control of cytostatic drug preparations-comparison of workflow and performance of Raman/UV and high-performance liquid chromatography coupled with diode array detection (HPLC-DAD).

Authors:  Lars M H Reinders; Martin D Klassen; Claudia Vom Eyser; Thorsten Teutenberg; Martin Jaeger; Torsten C Schmidt; Jochen Tuerk
Journal:  Anal Bioanal Chem       Date:  2021-02-23       Impact factor: 4.142

2.  Flexible Digitization of Highly Individualized Workflows Demonstrated Through the Quality Control of Patient-Specific Cytostatic Application Bags: Digitization from the Perspective of Small and Medium-Sized Laboratories.

Authors:  Max Jochums; Lars M H Reinders; Jochen Tuerk; Thorsten Teutenberg
Journal:  Adv Biochem Eng Biotechnol       Date:  2022       Impact factor: 2.768

  2 in total

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