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Literature DB >> 26923038

A contact-lens-on-a-chip companion diagnostic tool for personalized medicine.

Allan Guan¹, Yi Wang², K Scott Phillips², Zhenyu Li¹.

Abstract

We present a novel, microfluidic platform that integrates human tears (1 μL) with commercial contact lens materials to provide personalized assessment of lens care solution performance. This device enabled the detection of significant differences in cleaning and disinfection outcomes between subjects and between biofilms vs. planktonic bacteria.

Entities: Gene Species

Mesh：

Year: 2016 PMID： 26923038 DOI： 10.1039/c6lc00034g

Source DB: PubMed Journal: Lab Chip ISSN： 1473-0189 Impact factor: 6.799

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Cited

5 in total

Review 1. 3D Microfabricated Scaffolds and Microfluidic Devices for Ocular Surface Replacement: a Review.

Authors: Elisabetta Prina; Pritesh Mistry; Laura E Sidney; Jing Yang; Ricky D Wildman; Marina Bertolin; Claudia Breda; Barbara Ferrari; Vanessa Barbaro; Andrew Hopkinson; Harminder S Dua; Stefano Ferrari; Felicity R A J Rose
Journal: Stem Cell Rev Rep Date: 2017-06 Impact factor: 5.739

A contact-lens-on-a-chip companion diagnostic tool for personalized medicine.

Review 1. 3D Microfabricated Scaffolds and Microfluidic Devices for Ocular Surface Replacement: a Review.

Review 2. Small-volume detection: platform developments for clinically-relevant applications.

3. Emerging Anti-Fouling Methods: Towards Reusability of 3D-Printed Devices for Biomedical Applications.

Review 4. Organoids and Microphysiological Systems: New Tools for Ophthalmic Drug Discovery.

5. A Method for Developing Novel 3D Cornea-on-a-Chip Using Primary Murine Corneal Epithelial and Endothelial Cells.