| Literature DB >> 26919421 |
Benjamin Czech1, Gregory J Hannon2.
Abstract
For a decade, mystery has surrounded the mechanisms by which piRNA biogenesis yields distinct size classes of small RNAs within individual PIWI proteins. In this issue of Cell, two studies shed light on this process, identifying conserved PARN-family exonucleases that trim piRNAs to their mature size in silkworms and C. elegans.Entities:
Year: 2016 PMID： 26919421 DOI： 10.1016/j.cell.2016.02.012
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582