Literature DB >> 26910697

Topical Application of Arnica and Mucopolysaccharide Polysulfate Attenuates Periorbital Edema and Ecchymosis in Open Rhinoplasty: A Randomized Controlled Clinical Study.

Gokce Simsek1, Elif Sari, Rahmi Kilic, Nuray Bayar Muluk.   

Abstract

BACKGROUND: The purpose of this study was to investigate the effects of local arnica and mucopolysaccharide polysulfate treatment on the regression of postoperative edema and ecchymosis in patients who have undergone open technique rhinoplasty.
METHOD: One hundred eight patients were included in the study. Participants were randomized into three groups, all of whom had undergone rhinoplasty. Group 1 (n = 36) received postoperative arnica cream treatment, and group 2 (n = 36) received postoperative mucopolysaccharide polysulfate cream treatment. Group 3 (n = 36, control group) consisted of patients who received no postoperative local treatments. Patients were evaluated for 24 hours on days 2, 5, 7, and 10 after the operation. For the evaluation of postoperative edema and ecchymosis, a scale ranging from 0 to 4 was used, and the groups were compared.
RESULTS: In groups 1 and 2, postoperative ecchymosis was significantly less than in the control group during postoperative days 1, 5, and 7 (p < 0.005). The regression of the edema was also more rapid in groups 1 and 2 than in the control group during evaluations on postoperative days 1, 5, and 7 (p < 0.005). Neither edema nor ecchymosis was significantly different between groups 1 and 2 (p > 0.005).
CONCLUSIONS: The authors' results suggest that a rapid regression of edema and ecchymosis may be achieved by local treatments of arnica and mucopolysaccharide polysulfate cream. In addition, there are no significant differences between these two treatment regimens. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, II.

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Year:  2016        PMID: 26910697     DOI: 10.1097/01.prs.0000479967.94459.1c

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   4.730


  7 in total

Review 1.  The effectiveness of postoperative intervention in patients after rhinoplasty: a meta-analysis.

Authors:  Ho Seok Lee; Ho Young Yoon; In Hye Kim; Se Hwan Hwang
Journal:  Eur Arch Otorhinolaryngol       Date:  2017-03-17       Impact factor: 2.503

2.  Integrative Medicine in Plastic Surgery: A Systematic Review of Our Literature.

Authors:  Qing Zhao Ruan; Austin D Chen; Bao Ngoc N Tran; Sherise Epstein; Eugene Y Fukudome; Adam M Tobias; Samuel J Lin; Bernard T Lee; Gloria Y Yeh; Dhruv Singhal
Journal:  Ann Plast Surg       Date:  2019-04       Impact factor: 1.539

3.  A topical heparinoid-containing product improves epidermal permeability barrier homeostasis in mice.

Authors:  Ye Yao; Pan Guo; Xiaoyue Feng; Chunping Shen; Junkai Huang; Jiechen Zhang; Peter M Elias; Lizhi Hu; Mao-Qiang Man
Journal:  Exp Dermatol       Date:  2019-07-04       Impact factor: 3.960

Review 4.  Modalities of Post-Rhinoplasty Edema and Ecchymosis Measurement: A Systematic Review.

Authors:  Marc Levin; Hedyeh Ziai; Michael Roskies
Journal:  Plast Surg (Oakv)       Date:  2021-04-22       Impact factor: 0.558

5.  Cytocompatibility Properties of an Herbal Compound Solution Support I n vitro Wound Healing.

Authors:  Peng Zhou; Vanessa Chrepa; Ioannis Karoussis; Michael A Pikos; Georgios A Kotsakis
Journal:  Front Physiol       Date:  2021-03-26       Impact factor: 4.566

6.  Efficacy and Safety of Mucopolysaccharide Polysulfate Cream for Non-Exudative Eczema: A Systematic Review and Meta-Analysis.

Authors:  Ming Li; Yan Li; Lujing Xiang; Linfeng Li
Journal:  Front Med (Lausanne)       Date:  2021-12-24

7.  Anti-oxidant Effect of High Dilutions of Arnica montana, Arsenicum Album, and Lachesis Mutus in Microglial Cells in Vitro.

Authors:  Anne Paumier; Justine Verre; Sandra Tribolo; Naoual Boujedaini
Journal:  Dose Response       Date:  2022-06-29       Impact factor: 2.623

  7 in total

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