Literature DB >> 26904430

Endoscopic thymectomy: a neurologist's perspective.

Roberta Ricciardi1, Franca Melfi1, Michelangelo Maestri1, Anna De Rosa1, Afroditi Petsa1, Marco Lucchi1, Alfredo Mussi1.   

Abstract

Myasthenia gravis (MG) is an autoimmune neuromuscular disease characterized by the presence of antibodies interacting at the neuromuscular junction (NMJ), resulting in loss of strength and severe exhaustibility of striated muscles. The abnormal production of these antibodies is triggered mainly in the thymus, and hence thymectomy in MG is considered a universally recommended treatment in order to improve the symptomatologic condition of this pathology. Currently, minimally invasive thymectomy using the Da Vinci robot system is certainly one of the most innovative techniques, performed in Pisa since 2001. This approach provides a valuable alternative to the traditional thymectomy through median sternotomy. The contribution of a neurologist is fundamental for preoperative patient selection and for the peri-operative clinical assistance in both approaches. We believe that in the robotic approach, the multidisciplinary collaboration between the neurologist, thoracic surgeon and anesthetist is important in reducing perioperative complications and ensuring a higher rate of complete remission or stable clinical improvement of MG.

Entities:  

Keywords:  Myasthenia gravis (MG); acetylcholine receptor antibodies (AchRAb); robotic thymectomy; thymic hyperplasia; thymoma

Year:  2016        PMID: 26904430      PMCID: PMC4740105          DOI: 10.3978/j.issn.2225-319X.2015.12.02

Source DB:  PubMed          Journal:  Ann Cardiothorac Surg        ISSN: 2225-319X


  29 in total

1.  Antibodies against muscle-specific kinase impair both presynaptic and postsynaptic functions in a murine model of myasthenia gravis.

Authors:  Shuuichi Mori; Sachiho Kubo; Takuyu Akiyoshi; Shigeru Yamada; Tsuyoshi Miyazaki; Harumi Hotta; Junzo Desaki; Masahiko Kishi; Tetsuro Konishi; Yuri Nishino; Atsuo Miyazawa; Naoki Maruyama; Kazuhiro Shigemoto
Journal:  Am J Pathol       Date:  2011-12-03       Impact factor: 4.307

2.  MYASTHENIA GRAVIS AND TUMORS OF THE THYMIC REGION: REPORT OF A CASE IN WHICH THE TUMOR WAS REMOVED.

Authors:  A Blalock; M F Mason; H J Morgan; S S Riven
Journal:  Ann Surg       Date:  1939-10       Impact factor: 12.969

3.  Anti-MuSK autoantibodies block binding of collagen Q to MuSK.

Authors:  Y Kawakami; M Ito; M Hirayama; K Sahashi; B Ohkawara; A Masuda; H Nishida; N Mabuchi; A G Engel; K Ohno
Journal:  Neurology       Date:  2011-10-19       Impact factor: 9.910

4.  Myasthenia gravis and thymectomy: many doubts and few certainties.

Authors:  Giuseppe Marulli; Federico Rea
Journal:  Eur J Cardiothorac Surg       Date:  2014-10-13       Impact factor: 4.191

5.  High-dose intravenous gammaglobulin for myasthenia gravis.

Authors:  P Gajdos; H Outin; D Elkharrat; D Brunel; P de Rohan-Chabot; J C Raphael; M Goulon; C Goulon-Goeau; E Morel
Journal:  Lancet       Date:  1984-02-18       Impact factor: 79.321

6.  Alternate-dy prednisone in a patient with myasthenia gravis.

Authors:  J R Warmolts; W K Engel; J N Whitaker
Journal:  Lancet       Date:  1970-12-05       Impact factor: 79.321

7.  PTPN22 and myasthenia gravis: replication in an Italian population and meta-analysis of literature data.

Authors:  Carlo Provenzano; Roberta Ricciardi; Flavia Scuderi; Maria Teresa Maiuri; Michelangelo Maestri; Francesca La Carpia; Antonella Sferrazza; Mariapaola Marino; Lucia Leone; Marco Lucchi; Alfredo Mussi; Marcella Zollino; Amelia Evoli; Emanuela Bartoccioni
Journal:  Neuromuscul Disord       Date:  2011-12-24       Impact factor: 4.296

8.  Experience with the "da Vinci" robotic system for thymectomy in patients with myasthenia gravis: report of 33 cases.

Authors:  Federico Rea; Giuseppe Marulli; Luigi Bortolotti; Paolo Feltracco; Andrea Zuin; Francesco Sartori
Journal:  Ann Thorac Surg       Date:  2006-02       Impact factor: 4.330

9.  Association of thymoma and myasthenia gravis: oncological and neurological results of the surgical treatment.

Authors:  Marco Lucchi; Roberta Ricciardi; Franca Melfi; Leonardo Duranti; Fulvio Basolo; Gerardo Palmiero; Luigi Murri; Alfredo Mussi
Journal:  Eur J Cardiothorac Surg       Date:  2009-02-23       Impact factor: 4.191

10.  Thoracoscopic thymectomy with the da Vinci robotic system for myasthenia gravis.

Authors:  Jens C Rückert; Mahmoud Ismail; Marc Swierzy; Holger Sobel; Patrik Rogalla; Andreas Meisel; Klaus D Wernecke; Ralph I Rückert; Joachim M Müller
Journal:  Ann N Y Acad Sci       Date:  2008       Impact factor: 5.691

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  5 in total

Review 1.  Robotically assisted thymectomy: a review of the literature.

Authors:  Antonia Gkouma
Journal:  J Robot Surg       Date:  2017-09-13

Review 2.  How to get the best from robotic thoracic surgery.

Authors:  Sara Ricciardi; Carmelina Cristina Zirafa; Federico Davini; Franca Melfi
Journal:  J Thorac Dis       Date:  2018-04       Impact factor: 2.895

3.  Who will benefit from thymectomy for myasthenia gravis? Is there any role for this procedure in elderly patients?

Authors:  Ryo Otsuka; Kazuhiro Ueda; Toshiki Tanaka; Junichi Murakami; Masataro Hayashi; Kimikazu Hamano
Journal:  Ann Transl Med       Date:  2019-01

4.  Magnesium sulfate reduces the rocuronium dose needed for satisfactory double lumen tube placement conditions in patients with myasthenia gravis.

Authors:  Shoujun Fei; Hengfu Xia; Xiaowei Chen; Dazhi Pang; Xuebing Xu
Journal:  BMC Anesthesiol       Date:  2019-08-31       Impact factor: 2.217

5.  Thymoma-associated myasthenia gravis: Clinical features and predictive value of antiacetylcholine receptor antibodies in the risk of recurrence of thymoma.

Authors:  Anna De Rosa; Marco Fornili; Michelangelo Maestri Tassoni; Melania Guida; Laura Baglietto; Loredana Petrucci; Antonio Chella; Franca Melfi; Marco Lucchi; Roberta Ricciardi
Journal:  Thorac Cancer       Date:  2020-11-03       Impact factor: 3.500

  5 in total

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