| Literature DB >> 26899574 |
Xiao-Liu Dong1, Shi-Jun Xu2, Li Zhang3, Xiu-Qing Zhang2, Ting Liu2, Qiu-Yan Gao4, Qing-Qiang Qian5, Bao-Liang Sun6, Ming-Feng Yang6.
Abstract
The objective of this study was to investigate the association between serum resistin levels and acute cerebral infarction (ACI). PubMed, SpringerLink, Wiley, EBSCO, Ovid, Web of Science, Wanfang, China National Knowledge Infrastructure, and VIP databases (last updated search in October 2014) were exhaustively searched, and data from the eligible studies were extracted and analyzed to assess the association between serum resistin levels and ACI. STATA software (version 12.0, Stata Corporation, College Station, TX, USA) was utilized for data analysis. Ten studies including 1829 ACI patients and 1557 healthy controls were eligible for inclusion in the meta-analysis. Our major result revealed that ACI patients exhibited higher serum resistin levels compared with healthy controls. Asubgroup analysis based on ethnicity showed a significant association between serum resistin levels and ACI in Asians, but surprisingly not in Caucasians. The results of our meta-analysis suggest that serum resistin levels are associated with an increased risk of ACI.Entities:
Keywords: Acute cerebral infarction; Acute cerebrovascular disease; Acute stroke; Adipocyte-specific secretory factor; Found in inflammatory zone 3; Resistin
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Year: 2016 PMID： 26899574 DOI： 10.1007/s12035-016-9751-3
Source DB: PubMed Journal: Mol Neurobiol ISSN： 0893-7648 Impact factor: 5.590