| Literature DB >> 26893226 |
Benjamin Owen1, Christopher Lowe2, Neil Ashton3, Parthasarathi Mandal4, Steven Rogers2, Wolfgang Wein5, Charles McCollum2, Alistair Revell4.
Abstract
The current criterion for surgical intervention in abdominal aortic aneurysms, based upon a maximal aortic diameter, is considered conservative due to the high mortality rate in case of rupture. The research community is actively investigating the use of computational mechanics tools combined with patient-specific imaging to help identify more accurate criteria. Widespread uptake of a successful metric will however be limited by the need for computed tomography, which is at present the primary image extraction method on account of the location and complex shape of the aneurysms. The use of three-dimensional ultrasound as the scanning method is more attractive on account of increased availability, reduced cost and reduced risk to patients. The suitability of three-dimensional ultrasound is assessed for this purpose in the present work; computational fluid dynamics simulations were performed on geometries obtained from the same patient using both ultrasound and computed tomography. The influence of different smoothing algorithms is investigated in the geometry preparation stage and Taubin's low-pass filter was found to best preserve geometry features. Laminar, Newtonian, steady-state simulation analysis identified haemodynamic characteristics to be qualitatively similar in terms of wall shear stress, velocity and vorticity. The study demonstrates the potential for three-dimensional ultrasound to be integrated into a more accessible patient-specific modelling tool able to identify the need for surgical intervention of abdominal aortic aneurysms. © IMechE 2016.Entities:
Keywords: Abdominal aortic aneurysms; computational fluid dynamics; patient specific; three-dimensional ultrasound
Mesh:
Year: 2016 PMID: 26893226 DOI: 10.1177/0954411915626742
Source DB: PubMed Journal: Proc Inst Mech Eng H ISSN: 0954-4119 Impact factor: 1.617